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Possibilities of optical fluorescence spectral decomposition of meibum
Russian Annals of OphthalmologyObjective. The is study evaluated the possibilities of using optical fluorescence to determine the components of meibum. Material and methods. Meibum samples from 16 volunteers were analyzed using fluorescence spectroscopy in the visible optical range.
T.N. Safonova +4 more
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The role of meibum proteins in the pathogenesis of meibomian gland dysfunction
Russian Annals of OphthalmologyProteins and lipids in the meibum help maintain the balanced chemical composition of the tear film. However, the secretion of the meibomian glands contains various protein fractions, the function and effects of which on the lipid profile remain incompletely understood. This literature review provides a description of the main proteins of the meibum and
T.N. Safonova, G.V. Zaitseva
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Development of the 4–3–2–1 Meibum Expressibility Scale
Eye & Contact Lens: Science & Clinical Practice, 2012With increased interest in the assessment of meibomian gland dysfunction and evaporative dry eye, there remains a deficit in simple, clinically applicable grading scales for gland expression. A new scale to assess meibum expressibility is described.A meibum expressibility scale was developed using a new standardized meibomian gland expression device ...
Jillian F, Meadows +3 more
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Surface properties and exponential stress relaxations of mammalian meibum films
European Biophysics Journal, 2016The surface properties of meibomian secretion (MGS), the major constituent of the tear film (TF) lipid layer, are of key importance for TF stability. The interfacial properties of canine, cMGS, and feline, fMGS, meibum films were studied using a Langmuir surface balance.
Petar, Eftimov +4 more
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Lipidomic Analysis of Human Meibum Using HPLC–MSn
2009High-pressure liquid chromatography-mass spectrometry (HPLC-MS) has become a de facto standard analytical tool in lipidomic analyses of complex biological samples. This technique offers the best combination of selectivity and sensitivity among the currently available analytical methods, and provides not only the retention times of analytes, but also ...
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[Analysis of meibum by gas chromatography-mass spectrometry].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2016To analyze and identify the meibum from healthy individuals and patients with meibomian gland dysfunction (MGD) by gas chromatography-mass spectrometry (GC-MS).Case-control study. The meibum from twenty healthy persons and nineteen MGD patients was separated and analyzed by GC-MS. GC conditions were: column: DB-5 MS (30 m × 0.25 mm × 0.25 µm) capillary
Xueqing, Dong +6 more
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[Changes in human meibum with meibomian gland dysfunction].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2015Meibomian gland dysfunction (MGD) is a common ocular surface disease, characterized by terminal duct obstruction and (or) qualitative and quantitative changes in the glandular secretion. Meibomian lipids are a mixture consisting of various lipids, and they form the lipid layer of tear film and play important roles in preventing the evaporation and ...
Xiaodan, Hu +3 more
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Meibum Lipid Composition and Conformation in Parkinsonism.
EC ophthalmologyPatients with Parkinson's disease (PD) exhibit unstable tear films. Tear film lipid composition and structure are related to tear film stability and dry eye and tear lipids have not been characterized in people with PD. The aim of this study is to characterize Meibum tear lipids in donors with PD using 1H-NMR and infrared spectroscopy.Three cohorts ...
Solomon, Blinchevsky +4 more
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