Results 1 to 10 of about 72,680 (235)
Chromosome architecture and low cohesion bias acrocentric chromosomes towards aneuploidy during mammalian meiosis [PDF]
Aneuploidy in eggs is a leading cause of miscarriages or viable developmental syndromes. Aneuploidy rates differ between individual chromosomes. For instance, chromosome 21 frequently missegregates, resulting in Down Syndrome.
Eirini Bellou+8 more
doaj +2 more sources
The enumeration of BPS bound states in string theory needs refinement. Studying partition functions of particles made from D-branes wrapped on algebraic Calabi-Yau 3-folds, and classifying states using split attractor flow trees, we extend the method for computing a refined BPS index, arXiv:0810.4301.
Walter Van Herck, Thomas Wyder
arxiv +5 more sources
Tackling Plant Meiosis: From Model Research to Crop Improvement
Genetic engineering and traditional plant breeding, which harnesses the natural genetic variation that arises during meiosis, will have key roles to improve crop varieties and thus deliver Food Security in the future. Meiosis, a specialized cell division
Christophe Lambing, Stefan Heckmann
exaly +3 more sources
Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes [PDF]
In mammals, oocytes are arrested in prophase of meiosis I for long periods of time. Prophase arrest is critical for reproduction because it allows oocytes to grow to their full size to support meiotic maturation and embryonic development. Prophase arrest
Shiya Cheng, Melina Schuh
doaj +2 more sources
METTL16 is Required for Meiotic Sex Chromosome Inactivation and DSB Formation and Recombination during Male Meiosis [PDF]
Meiosis in males is a critical process that ensures complete spermatogenesis and genetic diversity. However, the key regulators involved in this process and the underlying molecular mechanisms remain unclear.
Lisha Yin+16 more
doaj +2 more sources
Polyploidy is a fundamental process in plant evolution. Understanding the polyploidy-associated effects on plant reproduction is essential for polyploid breeding program. In the present study, our cytological analysis firstly demonstrated that an overall
Janeen Braynen, S Odaka, S Oda
exaly +3 more sources
Two mechanisms drive pronuclear migration in mouse zygotes
In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear.
Kathleen Scheffler+6 more
doaj +1 more source
Sexual reproduction requires the production of haploid gametes (sperm and egg) with only one copy of each chromosome; fertilization then restores the diploid chromosome content in the next generation. This reduction in genetic content is accomplished during a specialized cell division called meiosis, in which two rounds of chromosome segregation follow
Hillers, Kenneth J+3 more
openaire +3 more sources
Meiosis is at the heart of Mendelian heredity. Recently, much progress has been made in the understanding of this process, in various organisms. In the last 15 years, the functional characterization of numerous genes involved in meiosis has dramatically deepened our knowledge of key events, including recombination, the cell cycle, and chromosome ...
Wayne Crismani+4 more
openaire +5 more sources
Sexual reproduction predominates among eukaryotic organisms on our planet. While debate continues over why this should be so, burgeoning genomic and functional information now allows us to begin to think reasonably about some of the events that may have occurred to make sex possible in the first place.
Villeneuve, Anne M., Hillers, Kenneth J.
openaire +3 more sources