Results 1 to 10 of about 157,342 (355)

Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I. [PDF]

PLoS Genetics, 2013
Sexually reproducing organisms halve their cellular ploidy during gametogenesis by undergoing a specialized form of cell division known as meiosis. During meiosis, a single round of DNA replication is followed by two rounds of nuclear divisions (referred
Sourav Sarkar, Rajesh T Shenoy, Jacob Z Dalgaard, Louise Newnham, Eva Hoffmann, Jonathan B A Millar, Prakash Arumugam   +6 more
doaj   +12 more sources

Two mechanisms drive pronuclear migration in mouse zygotes

Nature Communications, 2021
In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear.
Kathleen Scheffler, Julia Uraji, Ida Jentoft, Tommaso Cavazza, Eike Mönnich, Binyam Mogessie, Melina Schuh   +6 more
doaj   +1 more source

Shugoshin1 may play important roles in separation of homologous chromosomes and sister chromatids during mouse oocyte meiosis. [PDF]

PLoS ONE, 2008
BACKGROUND: Homologous chromosomes separate in meiosis I and sister chromatids separate in meiosis II, generating haploid gametes. To address the question why sister chromatids do not separate in meiosis I, we explored the roles of Shogoshin1 (Sgo1) in ...
Shen Yin, Jun-Shu Ai, Li-Hong Shi, Liang Wei, Ju Yuan, Ying-Chun Ouyang, Yi Hou, Da-Yuan Chen, Heide Schatten, Qing-Yuan Sun   +9 more
doaj   +1 more source

A PP2A-B56—Centered View on Metaphase-to-Anaphase Transition in Mouse Oocyte Meiosis I

Cells, 2020
Meiosis is required to reduce to haploid the diploid genome content of a cell, generating gametes—oocytes and sperm—with the correct number of chromosomes.
Leonor Keating, Sandra A. Touati, Katja Wassmann   +2 more
doaj   +1 more source

A Novel Meiosis-Related lncRNA, Rbakdn, Contributes to Spermatogenesis by Stabilizing Ptbp2

Frontiers in Genetics, 2021
Spermatocyte meiosis is the cornerstone of mammalian production. Thousands of long noncoding RNAs (lncRNAs) have been reported to be functional in various cellular processes, but the function of lncRNAs in meiosis remains largely unknown.
Wensheng Liu, Yinan Zhao, Xiaohua Liu, Xiaoya Zhang, Jiancheng Ding, Yang Li, Yingpu Tian, Haibin Wang, Wen Liu, Wen Liu, Zhongxian Lu, Zhongxian Lu, Zhongxian Lu   +12 more
doaj   +1 more source

Separase Is Required for Homolog and Sister Disjunction during Drosophila melanogaster Male Meiosis, but Not for Biorientation of Sister Centromeres. [PDF]

PLoS Genetics, 2016
Spatially controlled release of sister chromatid cohesion during progression through the meiotic divisions is of paramount importance for error-free chromosome segregation during meiosis.
Ariane C Blattner, Soumya Chaurasia, Bruce D McKee, Christian F Lehner   +3 more
doaj   +1 more source

Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1 [PDF]

, 2015
A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases.
A Alcasabas, A Emili, A Traven, AA Ali, Alastair S. Goldman, Ana Penedos, Anthony L. Johnson, B Argunhan, C Chuang, D Bishop, D Durocher, D Durocher, D Lydall, D Ontoso, D Woltering, DK Bishop, Emily Strong, H Cartagena-Lirola, H Lee, H Niu, H Niu, H Tsubouchi, HY Wu, I Acosta, J Falk, J Harper, J Melo, JA Carballo, JA Carballo, JA Carballo, Jesús A. Carballo, JM Bailis, JP Lao, K Hofmann, L Wan, L Xu, M Shinohara, MB Yaffe, Michael Lichten, NM Hollingsworth, NM Hollingsworth, R Suhandynata, Rita S. Cha, RS Cha, S Gray, T Allers, T de los Santos, T Tougan, T Usui, V Busygina, Y Sanchez, YH Lo   +51 more
core   +15 more sources

The Chromatin Protein DUET/MMD1 Controls Expression of the Meiotic Gene TDM1 during Male Meiosis in Arabidopsis. [PDF]

PLoS Genetics, 2015
Meiosis produces haploid cells essential for sexual reproduction. In yeast, entry into meiosis activates transcription factors which trigger a transcriptional cascade that results in sequential co-expression of early, middle and late meiotic genes ...
Sébastien Andreuzza, Bindu Nishal, Aparna Singh, Imran Siddiqi   +3 more
doaj   +1 more source

Insights into the identification and evolutionary conservation of key genes in the transcriptional circuits of meiosis initiation and commitment in budding yeast

FEBS Open Bio, 2023
Initiation of meiosis in budding yeast does not commit the cells for meiosis. Thus, two distinct signaling cascades may differentially regulate meiosis initiation and commitment in budding yeast.
Deepyaman Das, Anis Ahmad Chaudhary, Mohamed A. M. Ali, Abdullah S. Alawam, Hironmoy Sarkar, Soumita Podder   +5 more
doaj   +1 more source

How to halve ploidy : lessons from budding yeast meiosis [PDF]

, 2012
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash, Kerr, Gary W., Sarkar, Sourav   +2 more
core   +1 more source