Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I. [PDF]
PLoS Genetics, 2013 Sexually reproducing organisms halve their cellular ploidy during gametogenesis by undergoing a specialized form of cell division known as meiosis. During meiosis, a single round of DNA replication is followed by two rounds of nuclear divisions (referred
Sourav Sarkar +6 more
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The Chromatin Protein DUET/MMD1 Controls Expression of the Meiotic Gene TDM1 during Male Meiosis in Arabidopsis. [PDF]
PLoS Genetics, 2015 Meiosis produces haploid cells essential for sexual reproduction. In yeast, entry into meiosis activates transcription factors which trigger a transcriptional cascade that results in sequential co-expression of early, middle and late meiotic genes ...
Sébastien Andreuzza +3 more
doaj +2 more sources
Nature Communications, 2016 Meiosis is a cell division program that produces haploid gametes and is initiated by a retinoic acid-dependent process. Here the authors report that a meiosis-specific protein, MEIOC, is upregulated in a retinoic acid-independent manner and is required ...
Emilie Abby +12 more
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m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis
Nature Communications, 2019 Ime4p is a yeast N6-methyladenosine (m6A) methyltransferase with an unknown role in meiosis. Rme1p is a repressor of meiosis. Here the authors show that Ime4p methylates RME1 3′ UTR to reduce its expression and enable meiosis, thus providing an example ...
G. Guy Bushkin +7 more
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Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes
Nature, 2015 During fertilization, an egg and a sperm fuse to form a new embryo. Eggs develop from oocytes in a process called meiosis. Meiosis in human oocytes is highly error-prone, and defective eggs are the leading cause of pregnancy loss and several genetic ...
Michał Pasternak +2 more
exaly +2 more sources
Regulation of the MLH1–MLH3 endonuclease in meiosis
Nature, 2020 Elda Cannavo +2 more
exaly +2 more sources
Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation
Cell Research, 2017 Ying Yang, Yu-Sheng Chen, Chao Liu
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Meiosis: Dances Between Homologs.
Annual Review of Genetics, 2023 The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation and, within individual chromosomes, by DNA crossing-over.
D. Zickler, N. Kleckner
semanticscholar +1 more source
Two mechanisms drive pronuclear migration in mouse zygotes
Nature Communications, 2021 In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear.
Kathleen Scheffler +6 more
doaj +1 more source
Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1 [PDF]
, 2015 A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases.
A Alcasabas +51 more
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