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Sexual reproduction requires the production of haploid gametes (sperm and egg) with only one copy of each chromosome; fertilization then restores the diploid chromosome content in the next generation. This reduction in genetic content is accomplished during a specialized cell division called meiosis, in which two rounds of chromosome segregation follow
Hillers, Kenneth J +3 more
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Meiosis is at the heart of Mendelian heredity. Recently, much progress has been made in the understanding of this process, in various organisms. In the last 15 years, the functional characterization of numerous genes involved in meiosis has dramatically deepened our knowledge of key events, including recombination, the cell cycle, and chromosome ...
Crismani, Wayne +2 more
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Sexual reproduction predominates among eukaryotic organisms on our planet. While debate continues over why this should be so, burgeoning genomic and functional information now allows us to begin to think reasonably about some of the events that may have occurred to make sex possible in the first place.
Villeneuve, Anne M., Hillers, Kenneth J.
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The present paper reviews our observations on the premeiotic DNA replication in Lilium and on the morphology and behaviour of chromosomes during the meiotic prophase in Schizophyllum, Lilium, Drosophila, Bombyx and Homo as revealed by three-dimensional reconstructions of synaptonemal complexes (SC).
S W, Rasmussen, P B, Holm
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The past five years have seen the dawn of an era of illumination in our understanding of how vertebrate meiosis is regulated. Much of the foundation for recent progress came from the enormous advances in elucidating the molecular regulation of mitotic cell division and yeast meiosis (reviewed in Uhlmann 2001, Petronczki et al.
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Degradation of mitotic cyclins is critical for exit from mitosis. Recent studies in budding yeast address the role of cyclin degradation in meiosis. Cyclin stabilization in meiosis I interferes with anaphase I spindle disassembly but, surprisingly, does not halt progression into meiosis II.
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Meiosis in Bougainvillea [PDF]
A query concerning the possibilities of crossing various horticultural varieties of Bougainvillea led me to examine meiosis in several of the more important ones available in Jamaica. Six varieties, Snow White, Formosa, Dark Purple, Ruby, Orange King and Royal Purple, were used.
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Meiosis: How Male Flies Do Meiosis [PDF]
In meiosis in male fruitflies, chromosome pairing events do not facilitate genetic exchange, but rather create bivalents that can be sequestered to discrete pockets of the prophase nucleus. This assignment of homologs to a common pocket likely facilitates the orientation of homologous centromeres to opposite poles.
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Double-strand breaks (DSBs) threaten chromosome integrity. The most accurate repair of DSBs is by homologous recombination (HR), catalyzed by recombination proteins such as Rad51. Three papers in this issue of Molecular Cell (Fasching et al., 2015; Kaur et al., 2015; Tang et al., 2015) now reveal the role of three of these proteins in budding yeast ...
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