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Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I. [PDF]
PLoS Genetics, 2013 Sexually reproducing organisms halve their cellular ploidy during gametogenesis by undergoing a specialized form of cell division known as meiosis. During meiosis, a single round of DNA replication is followed by two rounds of nuclear divisions (referred
Sourav Sarkar +6 more
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Regulation of the MLH1–MLH3 endonuclease in meiosis [PDF]
Nature, 2020 Elda Cannavo +2 more
exaly +2 more sources
WormBook, 2017 Sexual reproduction requires the production of haploid gametes (sperm and egg) with only one copy of each chromosome; fertilization then restores the diploid chromosome content in the next generation. This reduction in genetic content is accomplished during a specialized cell division called meiosis, in which two rounds of chromosome segregation follow
Hillers, Kenneth J +3 more
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Two mechanisms drive pronuclear migration in mouse zygotes
Nature Communications, 2021 In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear.
Kathleen Scheffler +6 more
doaj +1 more source
Hereditas, 2009 The present paper reviews our observations on the premeiotic DNA replication in Lilium and on the morphology and behaviour of chromosomes during the meiotic prophase in Schizophyllum, Lilium, Drosophila, Bombyx and Homo as revealed by three-dimensional reconstructions of synaptonemal complexes (SC).
S W, Rasmussen, P B, Holm
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Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1 [PDF]
, 2015 A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases.
A Alcasabas +51 more
core +15 more sources
Shugoshin1 may play important roles in separation of homologous chromosomes and sister chromatids during mouse oocyte meiosis. [PDF]
PLoS ONE, 2008 BACKGROUND: Homologous chromosomes separate in meiosis I and sister chromatids separate in meiosis II, generating haploid gametes. To address the question why sister chromatids do not separate in meiosis I, we explored the roles of Shogoshin1 (Sgo1) in ...
Shen Yin +9 more
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A PP2A-B56—Centered View on Metaphase-to-Anaphase Transition in Mouse Oocyte Meiosis I
Cells, 2020 Meiosis is required to reduce to haploid the diploid genome content of a cell, generating gametes—oocytes and sperm—with the correct number of chromosomes.
Leonor Keating +2 more
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A Novel Meiosis-Related lncRNA, Rbakdn, Contributes to Spermatogenesis by Stabilizing Ptbp2
Frontiers in Genetics, 2021 Spermatocyte meiosis is the cornerstone of mammalian production. Thousands of long noncoding RNAs (lncRNAs) have been reported to be functional in various cellular processes, but the function of lncRNAs in meiosis remains largely unknown.
Wensheng Liu +12 more
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Journal of Experimental Botany, 2012 Meiosis is at the heart of Mendelian heredity. Recently, much progress has been made in the understanding of this process, in various organisms. In the last 15 years, the functional characterization of numerous genes involved in meiosis has dramatically deepened our knowledge of key events, including recombination, the cell cycle, and chromosome ...
Crismani, Wayne +2 more
openaire +3 more sources