Results 41 to 50 of about 110,882 (357)

TDM1 Regulation Determines the Number of Meiotic Divisions. [PDF]

open access: yesPLoS Genetics, 2016
Cell cycle control must be modified at meiosis to allow two divisions to follow a single round of DNA replication, resulting in ploidy reduction. The mechanisms that ensure meiosis termination at the end of the second and not at the end of first division
Marta Cifuentes   +12 more
doaj   +1 more source

Separase Control and Cohesin Cleavage in Oocytes: Should I Stay or Should I Go?

open access: yesCells, 2022
The key to gametogenesis is the proper execution of a specialized form of cell division named meiosis. Prior to the meiotic divisions, the recombination of maternal and paternal chromosomes creates new genetic combinations necessary for fitness and ...
Katja Wassmann
doaj   +1 more source

Focus on Meiosis [PDF]

open access: yesReproduction, 2005
The past five years have seen the dawn of an era of illumination in our understanding of how vertebrate meiosis is regulated. Much of the foundation for recent progress came from the enormous advances in elucidating the molecular regulation of mitotic cell division and yeast meiosis (reviewed in Uhlmann 2001, Petronczki et al.
openaire   +2 more sources

Spo13 prevents premature cohesin cleavage during meiosis [version 1; peer review: 2 approved, 1 approved with reservations]

open access: yesWellcome Open Research, 2019
Background: Meiosis produces gametes through two successive nuclear divisions, meiosis I and meiosis II. In contrast to mitosis and meiosis II, where sister chromatids are segregated, during meiosis I, homologous chromosomes are segregated. This requires
Stefan Galander   +3 more
doaj   +1 more source

Mechanisms of Oocyte Maturation and Related Epigenetic Regulation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins-induced ovulation happens. Once meiosis gets started, the oocytes undergo
Meina He   +8 more
doaj   +1 more source

The Arabidopsis Cdk1/Cdk2 homolog CDKA;1 controls chromosome axis assembly during plant meiosis

open access: yesEMBO Journal, 2019
Meiosis is key to sexual reproduction and genetic diversity. Here, we show that the Arabidopsis cyclin‐dependent kinase Cdk1/Cdk2 homolog CDKA;1 is an important regulator of meiosis needed for several aspects of meiosis such as chromosome synapsis.
C. Yang   +14 more
semanticscholar   +1 more source

The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice

open access: yesScience Advances, 2019
The histone modification reader ZCWPW1 guides male meiosis prophase I. Meiosis is a specialized type of cell division that creates haploid germ cells and ensures their genetic diversity through homologous recombination.
Miao Li   +17 more
semanticscholar   +1 more source

Distinct and Overlapping Requirements for Cyclins A, B, and B3 in Drosophila Female Meiosis

open access: yesG3: Genes, Genomes, Genetics, 2016
Meiosis, like mitosis, depends on the activity of the cyclin dependent kinase Cdk1 and its cyclin partners. Here, we examine the specific requirements for the three mitotic cyclins, A, B, and B3 in meiosis of Drosophila melanogaster.
Mohammed Bourouh   +5 more
doaj   +1 more source

Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. [PDF]

open access: yesPLoS Genetics, 2014
Cohesins are important for chromosome structure and chromosome segregation during mitosis and meiosis. Cohesins are composed of two structural maintenance of chromosomes (SMC1-SMC3) proteins that form a V-shaped heterodimer structure, which is bridged by
Jessica Hopkins   +8 more
doaj   +1 more source

Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I

open access: yesJournal of Cell Biology, 2019
Meiosis with a single round of DNA replication and two successive rounds of chromosome segregation requires specific cyclins associated with cyclin-dependent kinases (CDKs) to ensure its fidelity.
Yufei Li   +16 more
semanticscholar   +1 more source

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