Results 41 to 50 of about 48,915 (171)

Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I

open access: yesJournal of Cell Biology, 2019
Meiosis with a single round of DNA replication and two successive rounds of chromosome segregation requires specific cyclins associated with cyclin-dependent kinases (CDKs) to ensure its fidelity.
Yufei Li   +16 more
semanticscholar   +1 more source

Distinct and Overlapping Requirements for Cyclins A, B, and B3 in Drosophila Female Meiosis

open access: yesG3: Genes, Genomes, Genetics, 2016
Meiosis, like mitosis, depends on the activity of the cyclin dependent kinase Cdk1 and its cyclin partners. Here, we examine the specific requirements for the three mitotic cyclins, A, B, and B3 in meiosis of Drosophila melanogaster.
Mohammed Bourouh   +5 more
doaj   +1 more source

Positive feedback of NDT80 expression ensures irreversible meiotic commitment in budding yeast. [PDF]

open access: yesPLoS Genetics, 2014
In budding yeast, meiotic commitment is the irreversible continuation of the developmental path of meiosis. After reaching meiotic commitment, cells finish meiosis and gametogenesis, even in the absence of the meiosis-inducing signal. In contrast, if the
Dai Tsuchiya, Yang Yang, Soni Lacefield
doaj   +1 more source

Separase Control and Cohesin Cleavage in Oocytes: Should I Stay or Should I Go?

open access: yesCells, 2022
The key to gametogenesis is the proper execution of a specialized form of cell division named meiosis. Prior to the meiotic divisions, the recombination of maternal and paternal chromosomes creates new genetic combinations necessary for fitness and ...
Katja Wassmann
doaj   +1 more source

The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis

open access: yesBiology, 2017
Mistakes during cell division frequently generate changes in chromosome content, producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal division to generate aneuploid cells.
T. Potapova, G. Gorbsky
semanticscholar   +1 more source

Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research, 2017
Background Gametes are generated through a specialized cell division called meiosis, in which ploidy is reduced by half because two consecutive rounds of chromosome segregation, meiosis I and meiosis II, occur without intervening DNA replication.
Colette Fox   +3 more
doaj   +1 more source

Haploid meiosis in Arabidopsis: double-strand breaks are formed and repaired but without synapsis and crossovers. [PDF]

open access: yesPLoS ONE, 2013
Two hallmark features of meiosis are i) the formation of crossovers (COs) between homologs and ii) the production of genetically-unique haploid spores that will fuse to restore the somatic ploidy level upon fertilization.
Marta Cifuentes   +4 more
doaj   +1 more source

Chromosome architecture and low cohesion bias acrocentric chromosomes towards aneuploidy during mammalian meiosis

open access: yesNature Communications
Aneuploidy in eggs is a leading cause of miscarriages or viable developmental syndromes. Aneuploidy rates differ between individual chromosomes. For instance, chromosome 21 frequently missegregates, resulting in Down Syndrome.
Eirini Bellou   +8 more
doaj   +1 more source

Regulation of meiotic entry and gonadal sex differentiation in the human: normal and disrupted signaling

open access: yesBiomolecular Concepts, 2014
Meiosis is a unique type of cell division that is performed only by germ cells to form haploid gametes. The switch from mitosis to meiosis exhibits a distinct sex-specific difference in timing, with female germ cells entering meiosis during fetal ...
Jørgensen Anne, Rajpert-De Meyts Ewa
doaj   +1 more source

Anastral spindle assembly and γ-tubulin in Drosophila oocytes

open access: yesBMC Cell Biology, 2011
Background Anastral spindles assemble by a mechanism that involves microtubule nucleation and growth from chromatin. It is still uncertain whether γ-tubulin, a microtubule nucleator essential for mitotic spindle assembly and maintenance, plays a role ...
Hallen Mark A, Endow Sharyn A
doaj   +1 more source

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