Results 51 to 60 of about 157,342 (355)
Positive feedback of NDT80 expression ensures irreversible meiotic commitment in budding yeast. [PDF]
PLoS Genetics, 2014 In budding yeast, meiotic commitment is the irreversible continuation of the developmental path of meiosis. After reaching meiotic commitment, cells finish meiosis and gametogenesis, even in the absence of the meiosis-inducing signal. In contrast, if the
Dai Tsuchiya, Yang Yang, Soni Lacefield
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Meiosis: How Male Flies Do Meiosis [PDF]
Current Biology, 2002 In meiosis in male fruitflies, chromosome pairing events do not facilitate genetic exchange, but rather create bivalents that can be sequestered to discrete pockets of the prophase nucleus. This assignment of homologs to a common pocket likely facilitates the orientation of homologous centromeres to opposite poles.
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Wellcome Open Research, 2017 Background Gametes are generated through a specialized cell division called meiosis, in which ploidy is reduced by half because two consecutive rounds of chromosome segregation, meiosis I and meiosis II, occur without intervening DNA replication.
Colette Fox +3 more
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Separase Control and Cohesin Cleavage in Oocytes: Should I Stay or Should I Go?
Cells, 2022 The key to gametogenesis is the proper execution of a specialized form of cell division named meiosis. Prior to the meiotic divisions, the recombination of maternal and paternal chromosomes creates new genetic combinations necessary for fitness and ...
Katja Wassmann
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Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one [PDF]
, 2007 Background The vast majority of oocytes formed in the fetal ovary do not survive beyond birth. Possible reasons for their loss include the elimination of non-viable genetic constitutions arising through meiosis, however, the ...
Ghafari , Fataneh +2 more
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Meiosis in male Drosophila [PDF]
Spermatogenesis, 2012 Meiosis entails sorting and separating both homologous and sister chromatids. The mechanisms for connecting sister chromatids and homologs during meiosis are highly conserved and include specialized forms of the cohesin complex and a tightly regulated homolog synapsis/recombination pathway designed to yield regular crossovers between homologous ...
Rihui Yan, Bruce D. McKee, Jui-He Tsai
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Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
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Nature CommunicationsAneuploidy in eggs is a leading cause of miscarriages or viable developmental syndromes. Aneuploidy rates differ between individual chromosomes. For instance, chromosome 21 frequently missegregates, resulting in Down Syndrome.
Eirini Bellou +8 more
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Haploid meiosis in Arabidopsis: double-strand breaks are formed and repaired but without synapsis and crossovers. [PDF]
PLoS ONE, 2013 Two hallmark features of meiosis are i) the formation of crossovers (COs) between homologs and ii) the production of genetically-unique haploid spores that will fuse to restore the somatic ploidy level upon fertilization.
Marta Cifuentes +4 more
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Mechanisms of Oocyte Maturation and Related Epigenetic Regulation
Frontiers in Cell and Developmental Biology, 2021 Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins-induced ovulation happens. Once meiosis gets started, the oocytes undergo
Meina He +8 more
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