Hydrodynamic mechanism for stable spindle positioning in meiosis II oocytes [PDF]
Cytoplasmic streaming, the persistent flow of fluid inside a cell, induces intracellular transport, which plays a key role in fundamental biological processes. In meiosis II mouse oocytes (developing egg cells) awaiting fertilisation, the spindle, which is the protein structure responsible for dividing genetic material in a cell, must maintain its ...
arxiv +1 more source
Spermatogenesis is a continuous and productive process supported by the self-renewal and differentiation of spermatogonial stem cells (SSCs), which arise from undifferentiated precursors known as gonocytes and are strictly controlled in a special 'niche'
Su-Ren Chen, Yi-Xun Liu
semanticscholar +1 more source
Background Gametes are generated through a specialized cell division called meiosis, in which ploidy is reduced by half because two consecutive rounds of chromosome segregation, meiosis I and meiosis II, occur without intervening DNA replication.
Colette Fox+3 more
doaj +1 more source
Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes
In mammals, oocytes are arrested in prophase of meiosis I for long periods of time. Prophase arrest is critical for reproduction because it allows oocytes to grow to their full size to support meiotic maturation and embryonic development. Prophase arrest
Shiya Cheng, Melina Schuh
doaj +1 more source
Two-Parameter Characterization of Chromosome-Scale Recombination Rate [PDF]
The genome-wide recombination rate ($RR$) of a species is often described by one parameter, the ratio between total genetic map length ($G$) and physical map length ($P$), measured in centiMorgans per Megabase (cM/Mb). The value of this parameter varies greatly between species, but the cause for these differences is not entirely clear.
arxiv +1 more source
Evolutionary mysteries in meiosis
Meiosis is a key event of sexual life cycles in eukaryotes. Its mechanistic details have been uncovered in several model organisms, and most of its essential features have received various and often contradictory evolutionary interpretations.
T. Lenormand+4 more
semanticscholar +1 more source
The Neoplasia as embryological phenomenon and its implication in the animal evolution and the origin of cancer. III. The role of flagellated cell fusion in the formation of the first animal and evolutionary clues to the Warburg effect [PDF]
Cytasters have been underestimated in terms of their potential relevance to embryonic development and evolution. From the perspective discussed herein, structures such as the multiciliated cells of comb rows and balancers supporting mineralized statoliths and macrocilia in Beroe ovata point to a past event of multiflagellate fusion in the origin of ...
arxiv
Causal graphical models in systems genetics: A unified framework for joint inference of causal network and genetic architecture for correlated phenotypes [PDF]
Causal inference approaches in systems genetics exploit quantitative trait loci (QTL) genotypes to infer causal relationships among phenotypes. The genetic architecture of each phenotype may be complex, and poorly estimated genetic architectures may compromise the inference of causal relationships among phenotypes.
arxiv +1 more source
Sexual Dimorphism in Mouse Meiosis
Meiosis is a highly conserved and essential process in gametogenesis in sexually reproducing organisms. However, there are substantial sex-specific differences within individual species with respect to meiosis-related chromatin reorganization ...
Rong Hua, Mingxi Liu
doaj +1 more source
Emotion recognition based on multi-modal electrophysiology multi-head attention Contrastive Learning [PDF]
Emotion recognition is an important research direction in artificial intelligence, helping machines understand and adapt to human emotional states. Multimodal electrophysiological(ME) signals, such as EEG, GSR, respiration(Resp), and temperature(Temp), are effective biomarkers for reflecting changes in human emotions.
arxiv