Results 221 to 230 of about 6,538,014 (290)
A diverse satellite DNA repertoire in <i>Limnoperna fortunei</i>: insights into genome structure and chromosomal organization. [PDF]
Castro JP +5 more
europepmc +1 more source
Elevated LncRNA LINC00966 Suppresses PDE2A to Impair Sperm Motility in Asthenozoospermia
This study identifies LINC00966 as an upregulated lncRNA in asthenozoospermia associated with reduced sperm quality. Linc00966 suppresses Pde2a, disrupts cGMP signaling, and promotes oxidative stress, thereby impairing spermatogenic cell viability and migration.
Bingrou Guo +14 more
wiley +1 more source
The E3 Ligase UBR5/Hyd Ensures Meiotic Fidelity Through Catalysis-Independent Regulation of β2-Tubulin in <i>Drosophila</i>. [PDF]
Zhou L +5 more
europepmc +1 more source
Though drive efficiency was highly influential to model outcomes, such parameters will likely be known prior to any experimental gene drive introductions. We conclude that understanding the ecological and life‐history characteristics specific to target populations will be critical to accurately predict gene drive outcomes and inform risk assessments ...
Matthew A. Combs +5 more
wiley +1 more source
Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik +10 more
wiley +1 more source
Functional analyses of homoeologous pericentromeric cohesion protective genes TaSGO1s during meiosis in Triticum aestivum. [PDF]
Hu K +7 more
europepmc +1 more source
ABSTRACT The RNA‐binding protein NANOS2 plays a crucial role in male gonocyte development and the maintenance of spermatogonial stem cells. In the absence of the Nanos2 gene (Nanos2‐KO), germ cells fail to enter G0 arrest and initiate the male differentiation program (including DNA methylation and the piRNA pathway), ultimately undergoing apoptosis ...
Yumiko Saga, Quan Wu
wiley +1 more source
COSA-1-SLX-4 interaction directly links crossover designation with Holliday junction resolution. [PDF]
Liu G +10 more
europepmc +1 more source
Revisiting the life cycle of Margalefidinium polykrikoides Group III
Abstract Dinoflagellates produce cysts as a strategy to withstand environmental stressors, with nutrient depletion generally considered a key trigger for cyst production. Resting cysts are thick‐walled, typically composed of one to several layers, and characterized by a prolonged dormancy period.
Eduardo Pérez‐Vega +3 more
wiley +1 more source

