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Distribution of meiotic recombination sites
Trends in Genetics, 2003Meiotic recombination generates gene conversion and crossover events that are distributed heterogeneously in the genome. Studies in yeast show that initiation of recombination, which occurs by the formation of DNA double-strand breaks, determines the distribution of gene conversion and crossover events that take place in nearby intervals.
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Meiotic recombination hotspots in plants
Biochemical Society Transactions, 2006Many studies have demonstrated that the distribution of meiotic crossover events along chromosomes is non-random in plants and other species with sexual reproduction. Large differences in recombination frequencies appear at several scales. On a large scale, regions of high and low rates of crossover have been found to alternate along the chromosomes in
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Mammalian meiotic recombination: a reexamination
Human Genetics, 1994Recombination nodules (RNs) are small electron-dense structures associated with the synaptonemal complex. Two types have been identified: early RNs present during zygonema-early pachynema, which are thought to be involved in gene conversion and synaptic initiation, and late RNs present during mid-to-late pachynema, which are thought to be involved in ...
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Cytological aspects of meiotic recombination
Experientia, 1994This article reviews current views on the mechanisms of meiotic homology searching and recombination. It discusses the relationship between molecular events at meiotic prophase and concomitant cytological processes. The role of the synaptonemal complex and other meiosis-specific structures is discussed.
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Role of ubiquitination in meiotic recombination repair
Science China Life Sciences, 2010Programmed and unprogrammed double-strand breaks (DSBs) often arise from such physiological requirements as meiotic recombination, and exogenous insults, such as ionizing radiation (IR). Due to deleterious impacts on genome stability, DSBs must be appropriately processed and repaired in a regulatory manner.
Li, Cui, Wei, Li
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Modulation of Meiotic Recombination
2014Meiotic recombination is one of the principal forces creating the genetic diversity that drives evolution and is the fundamental instrument underlying most crop breeding programmes. A greater understanding of the control of recombination in crop plants would enable manipulation of this process to improve the speed and accuracy of plant breeding.
Ramsay, Luke +2 more
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Signaling-mediated meiotic recombination in plants
Current Opinion in Plant Biology, 2019Meiotic recombination provides genetic diversity in populations and ensures accurate homologous chromosome segregation for genome integrity. During meiosis, recombination processes, from DNA double strand breaks (DSBs) to crossover formation are tightly linked to higher order chromosome structure, including chromatid cohesion, axial element formation ...
Jaeil, Kim, Kyuha, Choi
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Origins of meiotic recombination
Nature Structural & Molecular Biology, 2021openaire +2 more sources
RNA-DNA hybrids regulate meiotic recombination
Cell Reports, 2021Liangran Zhang, Lin Liu, Xiao Yang
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