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Meiotic and Mitotic Recombination in Meiosis [PDF]
Genetics, 2013 Abstract Meiotic crossovers facilitate the segregation of homologous chromosomes and increase genetic diversity. The formation of meiotic crossovers was previously posited to occur via two pathways, with the relative use of each pathway varying between organisms; however, this paradigm could not explain all crossovers, and many of the ...
Jeff Sekelsky
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Divergence and conservation of the meiotic recombination machinery
Nature Reviews Genetics, 2023Sexually reproducing eukaryotes use recombination between homologous chromosomes to promote chromosome segregation during meiosis. Meiotic recombination is almost universally conserved in its broad strokes, but specific molecular details often differ considerably between taxa, and the proteins that constitute the recombination machinery show ...
Scott Keeney
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Meiotic recombination in yeast
Current Opinion in Genetics & Development, 1993Over the past several years, the yeast Saccharomyces cerevisiae has proven to be an extremely useful model system for understanding how cells acquire high recombinational ability during meiosis. Due to recent advances in the physical monitoring of DNA intermediates during meiosis, new cytological methods for visualization of chromosomes during pairing ...
C L, Atcheson, R E, Esposito
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Meiotic Recombination: Mixing It Up in Plants
Annual Review of Plant Biology, 2018Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents between homologous chromosomes (homologs) and their subsequent proper segregation.
Yingxiang Wang, Gregory P Copenhaver
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VARIATION IN HUMAN MEIOTIC RECOMBINATION
Annual Review of Genomics and Human Genetics, 2004▪ Abstract As recently as 20 years ago, there was relatively little information about the number and distribution of recombinational events in human meiosis, and we knew virtually nothing about factors affecting patterns of recombination. However, the generation of a variety of linkage-based genetic mapping tools and, more recently, cytological ...
Audrey, Lynn +2 more
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Recombination: Meiotic Recombination in Fungi
1997New combinations of genetic material are generated by the molecular process of genetic recombination. Recombination can affect all types of DNA: nuclear (mitosis and meiosis), organellar and plasmid DNA. Mitotic recombination is rare compared to meiotic recombination and appears to involve a less complex process (Esposito et al.
Heike Röhr, Ulf Stahl, Ursula Kües
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Meiotic Recombination and Crossovers in Plants
2008Efforts have been made in recent years to clarify molecular meiotic processes in a large variety of higher eukaryotes. In plants, such studies have enjoyed a boom in the last years with the use of Arabidopsis thaliana together with maize, rice and tomato as model systems.
A De, Muyt +3 more
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Distribution of meiotic recombination sites
Trends in Genetics, 2003Meiotic recombination generates gene conversion and crossover events that are distributed heterogeneously in the genome. Studies in yeast show that initiation of recombination, which occurs by the formation of DNA double-strand breaks, determines the distribution of gene conversion and crossover events that take place in nearby intervals.
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Meiotic recombination hotspots in plants
Biochemical Society Transactions, 2006Many studies have demonstrated that the distribution of meiotic crossover events along chromosomes is non-random in plants and other species with sexual reproduction. Large differences in recombination frequencies appear at several scales. On a large scale, regions of high and low rates of crossover have been found to alternate along the chromosomes in
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Mammalian meiotic recombination: a reexamination
Human Genetics, 1994Recombination nodules (RNs) are small electron-dense structures associated with the synaptonemal complex. Two types have been identified: early RNs present during zygonema-early pachynema, which are thought to be involved in gene conversion and synaptic initiation, and late RNs present during mid-to-late pachynema, which are thought to be involved in ...
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