Results 61 to 70 of about 62,976 (282)

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read‐Through Transcription, and Intragenic Contacts

open access: yesAdvanced Science, EarlyView.
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang   +5 more
wiley   +1 more source

Características físico-químicas de amostras de méis de Apis mellifera L., 1758 (Hymenoptera, Apidae) da região da Chapada do Araripe, município de Santana do Cariri, Estado do Ceará

open access: yesBoletim de Indústria Animal, 2013
A diversidade de floradas no sertão nordestino favorece a produção de méis com características bastante diferentes conforme o local e a época do ano em que foram produzidos.
Carolina Maranhão Fernandes de Arruda   +3 more
doaj  

Feasibility and acceptability of a beverage intervention for Hispanic adults: a protocol for a pilot randomized controlled trial

open access: yesNutrition Journal, 2018
Background In the U.S., Hispanics have among the highest rates of overweight and obesity when compared to other racial/ethnic groups placing them at a greater risk for obesity-related disease.
Kristin E. Morrill   +7 more
doaj   +1 more source

Mel-Wiener Filter for Mel-LPC Based Speech Recognition

open access: yesIEICE Transactions on Information and Systems, 2007
This paper proposes a Mel-Wiener filter to enhance Mel-LPC spectra in the presence of additive noise. The transfer function of the proposed filter is defined by using a first-order all-pass filter instead of unit delay. The filter coefficients are estimated based on minimization of the sum of the square error on the linear frequency scale without ...
Kazumasa Yamamoto   +2 more
openaire   +2 more sources

Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis

open access: yesAdvanced Science, EarlyView.
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard   +13 more
wiley   +1 more source

Comercio internacional y crecimiento económico: ¿cómo influyen en el hambre de América Latina?

open access: yesNutrición Hospitalaria
Dos de las recetas que se plantean en el espectro político para fomentar el desarrollo económico y social son el impulso del crecimiento económico y el comercio internacional.
J. Guardiola, J. Bernal Rivas
doaj  

Composição físico-química de amostra de méis de Apis mellifera L. do Estado de Tocantins, Brasil

open access: yesBoletim de Indústria Animal, 2013
A presente pesquisa, desenvolvida com amostras de méis de Apis mellifera coletadas diretamente dos produtores de diversos municípios do Estado de Tocantins, Brasil, teve o objetivo de verificar, com base em características físico-químicas, como se ...
Luís Carlos Marchini   +3 more
doaj  

Imputation strategies when a continuous outcome is to be dichotomized for responder analysis: a simulation study

open access: yesBMC Medical Research Methodology, 2019
Background In many clinical trials continuous outcomes are dichotomized to compare proportions of patients who respond. A common and recommended approach to handling missing data in responder analysis is to impute as non-responders, despite known biases.
Lysbeth Floden, Melanie L. Bell
doaj   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

open access: yesAdvanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li   +17 more
wiley   +1 more source

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