Results 221 to 230 of about 57,304 (322)

Area integrity index with random rearrangement (AIIRR): A new concept for quantifying disruptive colorations

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract Disruptive coloration is one of the camouflaging strategies that use conspicuous coloration patterns to destroy the visual integrity of an object and interfere with the observer's visual perception. Such conspicuous coloration often divides the entire shape of the object into multiple areas, increasing the disruption effect. Here, we introduce
Masahiko Tanahashi   +2 more
wiley   +1 more source

Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging

open access: yesAging Cell, EarlyView.
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang   +22 more
wiley   +1 more source

Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells

open access: yesAging Cell, EarlyView.
Expression of HIRA in embryonic melanoblasts is required for proper epigenetic programing and lineage differentiation. Although HIRA deficiency results in a mild phenotype at birth and young adulthood, the melanocytic lineage is sensitive to proliferative challenge, prone to loss of stem cells and dramatically accelerated hair greying in later life ...
Farah Jaber‐Hijazi   +20 more
wiley   +1 more source

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