Results 1 to 10 of about 6,578 (220)

Structural Investigation of DHICA Eumelanin Using Density Functional Theory and Classical Molecular Dynamics Simulations

Molecules, 2022
Eumelanin is an important pigment, for example, in skin, hair, eyes, and the inner ear. It is a highly heterogeneous polymer with 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and 5,6-dihydroxyindole (DHI) building blocks, of which DHICA is reported as ...
Sepideh Soltani, Shahin Sowlati-Hashjin, Conrard Giresse Tetsassi Feugmo, Mikko Karttunen   +3 more
doaj   +2 more sources

Investigation of Eumelanin Biosynthesis in Gluconacetobacter tumulisoli FBFS 97: A Novel Insight into a Bacterial Melanin Producer

Microorganisms
Acetic acid bacteria (AAB) are a group of bacteria, most of which can produce pigments. However, the mechanism of pigment production by AAB is unclear.
Jiayun Song, Yanqin Ma, Zhenzhen Xie, Fusheng Chen   +3 more
doaj   +2 more sources

Exploring the Charge Transport of a Natural Eumelanin for Sustainable Technologies

ACS Applied Bio Materials, 2023
Eumelanin, the main quinone-based biomaterial of the melanin family of compounds, is emerging as a model for medical and sustainable electronic interfaces due to its biocompatibility, biodegradability, and transducing abilities.
CARLOS Cesar Bof Bufon, Sinan Bayram, João Vitor Paulin   +2 more
exaly   +2 more sources

Aspacochioside C from Asparagus cochinchinensis attenuates eumelanin synthesis via inhibition of TRP2 expression

Scientific Reports, 2023
Aspacochioside C (ACC) is a steroidal saponin isolated from Asparagus cochinchinensis. Steroidal saponins, such as pseudoprotodioscin and dioscin, are known to inhibit melanogenesis, but the role of ACC in melanogenesis remains unknown.
Silvia Yunmam, Hae Ran Lee, Seong Min Hong, Ji-Young Kim, Tong Ho Kang, Ai Young Lee, Dae Sik Jang, Sun Yeou Kim   +7 more
doaj   +2 more sources

Evidence of Unprecedented High Electronic Conductivity in Mammalian Pigment Based Eumelanin Thin Films After Thermal Annealing in Vacuum

Frontiers in Chemistry, 2019
Melanin denotes a variety of mammalian pigments, including the dark electrically conductive eumelanin and the reddish, sulfur-containing, pheomelanin.
Ludovico Migliaccio, Paola Manini, Davide Altamura, Cinzia Giannini, Paolo Tassini, Maria Grazia Maglione, Carla Minarini, Alessandro Pezzella   +7 more
doaj   +2 more sources

Identification of L-Cysteinamide as a Potent Inhibitor of Tyrosinase-Mediated Dopachrome Formation and Eumelanin Synthesis

Antioxidants, 2021
The purpose of this study is to identify amino acid derivatives with potent anti-eumelanogenic activity. First, we compared the effects of twenty different amidated amino acids on tyrosinase (TYR)-mediated dopachrome formation in vitro and melanin ...
Hyun Kyung Lee, Jae Won Ha, Yun Jeong Hwang, Yong Chool Boo   +3 more
doaj   +2 more sources

Physiological Roles of Eumelanin- and Melanogenesis-Associated Diseases: A Look at the Potentialities of Engineered and Microbial Eumelanin in Clinical Practice

Bioengineering
This paper aims to highlight the physiological actions exerted by eumelanin present in several organs/tissues of the human body and to rationalise the often conflicting functional roles played by this biopolymer on the basis of its peculiar properties ...
Maria Letizia Terranova
exaly   +3 more sources

Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications [PDF]

Journal of Fungi
Natural melanin biopolymers exhibit a variety of biological activities, but their commercial development is constrained by numerous factors, including high costs, unsustainable sources, the use of harmful solvents during extraction, and low extraction ...
Jiandong Tang, Hebin Shen, Wenyu Lv, Jingxuan Zhang, Junsheng Fu   +4 more
doaj   +2 more sources

Eumelanin electrodes in buffered aqueous media at different pH values

Electrochimica Acta, 2020
Eumelanin, a quinone-based biomacromolecule, is the most common form of the biopigment melanin in the human body. Eumelanin has attracted great interest due to its physicochemical properties, such as metal-ion chelation, free radical scavenging ...
Clara Santato, Abdelaziz Gouda, Francesca Soavi   +2 more
exaly   +2 more sources

MC1R: Front and Center in the Bright Side of Dark Eumelanin and DNA Repair

International Journal of Molecular Sciences, 2018
Melanin, the pigment produced by specialized cells, melanocytes, is responsible for skin and hair color. Skin pigmentation is an important protective mechanism against the DNA damaging and mutagenic effects of solar ultraviolet radiation (UV).
Zalfa Abdel-Malek, Viki B Swope, Abdel-Malek Zalfa A   +2 more
exaly   +2 more sources