Results 111 to 120 of about 14,691 (270)
Two proteases defining a melanization cascade in the immune system of Drosophila [PDF]
The melanization reaction is used as an immune mechanism in arthropods to encapsulate and kill microbial pathogens. In Drosophila, the serpin Spn27A regulates melanization apparently by inhibiting the protease that activates phenoloxidase, the key enzyme
Lemaitre, Bruno +3 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2020 Animals have developed numerous strategies to contend with environmental pressures. We observed that the same adaptation strategy may be used repeatedly by one species in response to a certain environmental challenge.
Yi Zhang +11 more
doaj +1 more source
The FEBS Journal, EarlyView.DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source
Ibis, EarlyView.High colour variability in animals has been associated with adaptability to environmental change. Establishing how such variability is distributed in time and space, and identifying environmental correlates, can help understand the processes driving it.
Kaspar Delhey +4 more
wiley +1 more source
Dissecting The Melanization Immune Response In The Malaria Vector Anopheles Gambiae
, 2021 Melanization is among the first lines of defense in arthropods following injury or infection. Manipulating mosquito melanization can influence vector competence for Plasmodium, compromise antifungal defense, and reduce longevity.
Sousa, Gregory Lee
core
PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
International Journal of Dermatology, EarlyView.This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
Epistatic QTLs for amoeba resistance and melanization.
, 2023 The offspring of the Bt22 × Ftc555-1 cross were subset by genotype at the chromosome 8 QTL, and QTL mapping was repeated for each subpopulation. Variation on chromosome 8 was excluded from consideration. The dotted lines indicate significance thresholds (
Sheng Sun (142836) +8 more
core +1 more source
Journal of Zoology, EarlyView.The Urban Heat Island Effect (UHI) can potentially subject insects to heat and desiccation stress and likely induce shifts in their cuticular hydrocarbon (CHC) profile. We expected that warmer urbanized areas favour longer chain length of hydrocarbons as well as higher abundance of n‐alkanes in three Hymenoptera species. We found that temperature, more
A. Ferrari +3 more
wiley +1 more source
A food color-based colorimetric assay for Cryptococcus neoformans laccase activity
Microbiology SpectrumCryptococcus neoformans is a fungal pathogen that causes cryptococcosis primarily in immunocompromised patients, such as those with HIV/AIDS. One survival mechanism of C.
Lia Sanchez Ramirez +2 more
doaj +1 more source
Developmental and Comparative Immunology, 2018 Melanization, mediated by the prophenoloxidase (proPO)‐activating system, is an important innate immune response in invertebrates. The implication of the proPO system in antiviral response and the suppression of host proPO activation by the viral protein
P. Sangsuriya +6 more
semanticscholar +1 more source