Results 31 to 40 of about 8,666 (209)

Identification of a Conserved Prophenoloxidase Activation Pathway in Cotton Bollworm Helicoverpa armigera

Frontiers in Immunology, 2020
Melanization is a prominent insect humoral response for encapsulation of and killing invading pathogens. It is mediated by a protease cascade composed of a modular serine protease (SP), and clip domain SPs (cSPs), which converts prophenoloxidase (PPO ...
Qianran Wang, Qianran Wang, Mengyi Yin, Mengyi Yin, Chuanfei Yuan, Chuanfei Yuan, Xijia Liu, Zhihong Hu, Zhen Zou, Zhen Zou, Zhen Zou, Manli Wang   +11 more
doaj   +1 more source

Role of Cln1 during melanization of Cryptococcus neoformans

Frontiers in Microbiology, 2015
Cryptococcus neoformans is an opportunistic fungal pathogen that has several well-described virulence determinants. A polysaccharide capsule and the ability to produce melanin are among the most important.
Rocío eGarcía-Rodas, Nuria eTrevijano-Contador, Elvira eRomán, Guilhem eJanbon, Frederique eMoyrand, Jesus ePla, Arturo eCasadevall, Oscar eZaragoza   +7 more
doaj   +1 more source

Tracheal melanic tattoo

Monaldi Archives for Chest Disease, 2015
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M. Mondoni, P. Carlucci, L. Boiocchi, S. Centanni   +3 more
openaire   +5 more sources

LAC2 Encoding a Secreted Laccase Is Involved in Appressorial Melanization and Conidial Pigmentation in Colletotrichum orbiculare

Molecular Plant-Microbe Interactions, 2012
Both Colletotrichum and Magnaporthe spp. develop appressoria pigmented with melanin, which is essential for fungal pathogenicity. 1,8-Dihydroxynaphthalene (1,8-DHN) is believed to be polymerized to yield melanin around the appresorial cell wall through ...
Shao Yu Lin, Shiho Okuda, Kyoko Ikeda, Tetsuro Okuno, Yoshitaka Takano   +4 more
doaj   +1 more source

More Than Black or White: Melanization and Toll Share Regulatory Serine Proteases in Drosophila.

Cell Reports, 2019
The melanization response is an important defense mechanism in arthropods. This reaction is mediated by phenoloxidases (POs), which are activated by complex extracellular serine protease (SP) cascades.
J. Dudzic, M. Hanson, I. Iatsenko, S. Kondo, B. Lemaître   +4 more
semanticscholar   +1 more source

Molecular identification and enzymatic properties of laccase2 from the diamondback moth Plutella xylostella (Lepidoptera: Plutellidae)

Journal of Integrative Agriculture, 2018
Laccase (EC 1.10.3.2) is known to oxidize various aromatic and nonaromatic compounds via a radical-catalyzed reaction, which generally includes two types of laccase, Lac1 and Lac2.
Zhen-gang LIU, Huan-huan WANG, Chao-bin XUE   +2 more
doaj   +1 more source

Late sporogonic stages of Plasmodium parasites are susceptible to the melanization response in Anopheles gambiae mosquitoes

Frontiers in Cellular and Infection Microbiology
The malaria-causing parasites have to complete a complex infection cycle in the mosquito vector that also involves attack by the insect’s innate immune system, especially at the early stages of midgut infection.
Suheir Zeineddine, Sana Jaber, Sally A. Saab, Johnny Nakhleh, George Dimopoulos, Mike A. Osta   +5 more
doaj   +1 more source

Higher temperature accelerates the aging-dependent weakening of the melanization immune response in mosquitoes

PLoS Pathogens
The body temperature of mosquitoes, like most insects, is dictated by the environmental temperature. Climate change is increasing the body temperature of insects and thereby altering physiological processes such as immune proficiency.
Lindsay E. Martin, J. Hillyer
semanticscholar   +1 more source

Cellular immunity and pathogen strategies in combative interactions involving Drosophila hosts and their endoparasitic wasps [PDF]

Invertebrate Survival Journal, 2010
Various cellular innate immune responses protect invertebrates from attack by eukaryotic pathogens. In insects, assessments of the factor(s) causing, or contributing to, pathogen mortality have long considered as toxic components certain molecules ...
A J Nappi
doaj   +1 more source

CLIPA7 Exhibits Pleiotropic Roles in the Anopheles gambiae Immune Response

Journal of Innate Immunity, 2022
Clip domain serine proteases and clip domain serine protease homologs (cSPHs) are key components of serine protease cascades that drive the melanization response.
Renée Zakhia, Mike A. Osta
doaj   +1 more source