Results 31 to 40 of about 14,691 (270)

Melanization slows the rapid movement of fungal necromass carbon and nitrogen into both bacterial and fungal decomposer communities and soils

mSystems, 2023
Microbial necromass contributes significantly to both soil carbon (C) persistence and ecosystem nitrogen (N) availability, but quantitative estimates of C and N movement from necromass into soils and decomposer communities are lacking.
François Maillard, Talia J Michaud, C. See, L. C. DeLancey, S. Blazewicz, Jeffrey A. Kimbrel, J. Pett‐Ridge, P. Kennedy   +7 more
semanticscholar   +1 more source

Insight into the structural hierarchy of the protease cascade that regulates the mosquito melanization response

bioRxiv, 2023
Serine protease cascades regulate important insect immune responses, including melanization and Toll pathway activation. In the context of melanization, central components of these cascades are clip domain serine proteases (CLIPs) including the catalytic,
S. Saab, Xiufeng Zhang, Suheir Zeineddine, Bianca Morejón, K. Michel, M. Osta   +5 more
semanticscholar   +1 more source

Glyphosate and Melanization

, 2021
Melanin is a black-brown pigment found throughout all kingdoms of life playing diverse roles including: UV protection, thermoregulation, oxidant scavenging, arthropod immunity, and microbial virulence.
Smith, D (via Mendeley Data)
core   +2 more sources

The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron sequestration and melanization

bioRxiv, 2023
Facultative endosymbiotic bacteria, such as Wolbachia and Spiroplasma species, are commonly found in association with insects and can dramatically alter their host physiology.
Alexandra Hrdina, Marina Serra Canales, A. Arias-Rojas, Dagmar Frahm, I. Iatsenko   +4 more
semanticscholar   +1 more source

An immune-responsive Serpin regulates the melanization cascade in Drosophila [PDF]

, 2016
In arthropods, the melanization reaction is associated with multiple host defense mechanism leading to the sequestration and killing of invading microorganisms.
이원재
core   +3 more sources

Galleria mellonella immune melanization is fungicidal during infection

Communications Biology, 2022
A key component of the insect immune response is melanin production, including within nodules, or aggregations of immune cells surrounding microbes. Melanization produces oxidative and toxic intermediates that limit microbial infections.
Daniel F. Q. Smith, Q. Dragotakes, Madhura Kulkarni, J. Hardwick, A. Casadevall   +4 more
semanticscholar   +1 more source

C-type lectin 4 regulates broad-spectrum melanization-based refractoriness to malaria parasites

PLoS Biology, 2022
Anopheles gambiae melanization-based refractoriness to the human malaria parasite Plasmodium falciparum has rarely been observed in either laboratory or natural conditions, in contrast to the rodent model malaria parasite Plasmodium berghei that can ...
M. Simões, Yuemei Dong, G. Mlambo, G. Dimopoulos   +3 more
semanticscholar   +1 more source

Melanization of Candida auris Is Associated with Alteration of Extracellular pH

bioRxiv, 2022
Candida auris is a recently emerged global fungal pathogen, which causes life-threatening infections, often in healthcare settings. C. auris infections are worrisome because the fungus is often resistant to multiple antifungal drug classes.
Daniel F. Q. Smith, Nathan J. Mudrak, Daniel Zamith-Miranda, L. Honorato, L. Nimrichter, Christine Chrissian, Barbara J Smith, G. Gerfen, R. Stark, J. Nosanchuk, A. Casadevall   +10 more
semanticscholar   +1 more source

Glyphosate inhibits melanization and increases susceptibility to infection in insects

PLoS Biology, 2021
Melanin, a black-brown pigment found throughout all kingdoms of life, has diverse biological functions including UV protection, thermoregulation, oxidant scavenging, arthropod immunity, and microbial virulence.
Daniel F. Q. Smith, E. Camacho, Raviraj Thakur, Alexander J. Barron, Yuemei Dong, G. Dimopoulos, N. Broderick, A. Casadevall   +7 more
semanticscholar   +1 more source

Prophenoloxidase of Odontotermes formosanus (Shiraki) (Blattodea: Termitidae) Is a Key Gene in Melanization and Has a Defensive Role during Bacterial Infection

International Journal of Molecular Sciences, 2022
Melanization mediated by the prophenoloxidase (PPO)-activating system is an important innate immunity to fight pathogens in insects. In this study, the in vitro time-dependent increase in the intensity of melanization and phenoloxidase (PO) activity from
Zhiqiang Wang, Jian-Xin Luo, K. Feng, Yujingyun Zhou, F. Tang   +4 more
semanticscholar   +1 more source