Results 81 to 90 of about 2,739 (191)
Korean Journal of Clinical Laboratory Science, 2021 This study was conducted to evaluate the dermal cytotoxicity of lead acetate (LA) and other heavy metal compounds, and the protective effect of Lespedeza bicolor (LB) extract on LA-induced cytotoxicity in cultured B16-/F10 melanoma cells.
Young-Mi Seo
doaj +1 more source
Ecological Entomology, EarlyView.The parasitoid‐associated polydnavirus CgPDV, but not venom alone, significantly increases the attractiveness of Pieris brassicae caterpillars to the hyperparasitoid Baryscapus galactopus at close range. Naturally parasitized caterpillars elicit stronger hyperparasitoid attraction than any injection treatment, indicating that additional factors beyond ...
Yuhan Liu +5 more
wiley +1 more source
Dissecting The Melanization Immune Response In The Malaria Vector Anopheles Gambiae
, 2021 Melanization is among the first lines of defense in arthropods following injury or infection. Manipulating mosquito melanization can influence vector competence for Plasmodium, compromise antifungal defense, and reduce longevity.
Sousa, Gregory Lee
core
Prophenoloxidase activation is required for survival to microbial infections in Drosophila.
PLoS Pathogens, 2014 The melanization reaction is a major immune response in Arthropods and involves the rapid synthesis of melanin at the site of infection and injury. A key enzyme in the melanization process is phenoloxidase (PO), which catalyzes the oxidation of phenols ...
Olivier Binggeli +3 more
doaj +1 more source
The FEBS Journal, EarlyView.DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source
Epistatic QTLs for amoeba resistance and melanization.
, 2023 The offspring of the Bt22 × Ftc555-1 cross were subset by genotype at the chromosome 8 QTL, and QTL mapping was repeated for each subpopulation. Variation on chromosome 8 was excluded from consideration. The dotted lines indicate significance thresholds (
Sheng Sun (142836) +8 more
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Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
The FEBS Journal, EarlyView.C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
Two proteases defining a melanization cascade in the immune system of Drosophila [PDF]
The melanization reaction is used as an immune mechanism in arthropods to encapsulate and kill microbial pathogens. In Drosophila, the serpin Spn27A regulates melanization apparently by inhibiting the protease that activates phenoloxidase, the key enzyme
Lemaitre, Bruno +3 more
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Insect Molecular Biology, EarlyView.Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto +2 more
wiley +1 more source
Melanism in cats; The fascinating phenomenon of melanism in big cats
, 2023 What is melanism in big cats? Melanism is a genetic condition that results in increased production of dark pigmentation in the skin, coat and eyes of animals. In big cats, this condition can result in an all-black coat called melanistic. This is caused by a mutation in the genes responsible for the production of melanin, the pigment that gives color to
openaire +1 more source