Results 91 to 100 of about 59,513 (188)

Melanocortin-4 Receptor in Fish: A Review

International Journal of Agricultural Science and Food Technology, 2017
The melanocortin-4 receptor (MC4R) belongs to the melanocortin system, has been well investigated in mammals. Which plays important roles in several physiological processes, such as regulating energy homeostasis, cachexia, cardiovascular function, glucose and lipid homeostasis, reproduction and sexual function, drug abuse, pain perception, brain ...
openaire   +1 more source

Melanocortin 4 receptor (MC4R) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Genetic variation in the SIM1 locus is associated with erectile dysfunction. [PDF]

, 2018
Erectile dysfunction affects millions of men worldwide. Twin studies support the role of genetic risk factors underlying erectile dysfunction, but no specific genetic variants have been identified. We conducted a large-scale genome-wide association study
Ahituv, Nadav, Hoffmann, Thomas J, Hotaling, James M, Jarvik, Gail P, Jorgenson, Eric, Matharu, Navneet, Palmer, Melody R, Shan, Jun, Thai, Khanh K, Van Den Eeden, Stephen K, Wessells, Hunter, Yin, Jie, Zhou, Xujia   +12 more
core  

Dimerization of melanocortin 4 receptor controls puberty onset and body size polymorphism. [PDF]

Front Endocrinol (Lausanne), 2023
Liu R, Friedrich M, Hemmen K, Jansen K, Adolfi MC, Schartl M, Heinze KG.   +6 more
europepmc   +1 more source

Molecular remodeling of the myocardium in mice with melanocortin-4 receptor deletion before cardiac function impairment. [PDF]

PLoS One
Wang X, Qi Y, Zhu Z, Wang C, Zhang Z, Jia H, Xia L, Meng K, Yuan J.   +8 more
europepmc   +1 more source

Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice. [PDF]

Sci Rep, 2023
Mori K, Okuma H, Nakamura S, Uchinuma H, Kaga S, Nakajima H, Ogawa Y, Tsuchiya K.   +7 more
europepmc   +1 more source

MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor. [PDF]

Nat Commun
Sohail I, Laurin SA, Kleinau G, Chunilal V, Morton A, Brenlla A, Kagiali ZCU, Blouin MJ, Tello JA, Beck-Sickinger AG, Lohse MJ, Scheerer P, Bouvier M, McCormick P, Annibale P, Biebermann H.   +15 more
europepmc   +1 more source

Modulating food intake by nasal application of peptides targeting melanocortin 4 receptor and ghrelin receptor systems. [PDF]

Brain Commun
Özbay B, Jülke EM, List M, Nowicki M, Els-Heindl S, Immig K, Mörl K, Bechmann I, Beck-Sickinger AG.   +8 more
europepmc   +1 more source

Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds. [PDF]

ACS Pharmacol Transl Sci, 2023
Muratspahić E, Aslanoglou D, White AM, Draxler C, Kozisek X, Farooq Z, Craik DJ, McCormick PJ, Durek T, Gruber CW.   +9 more
europepmc   +1 more source

Improving the diagnosis of hyperphagia in melanocortin-4 receptor pathway diseases. [PDF]

Obesity (Silver Spring)
Abuzzahab MJ, Dubern B, Goldstone AP, Haqq AM, Heymsfield SB, Miller JL, Richards J, Wabitsch M, Yanovski JA.   +8 more
europepmc   +1 more source