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MELANOCYTE-STIMULATING HORMONE AND PARKINSONISM

The Lancet, 1973
Abstract Circulating b-melanocyte-stimulating-hormone (β-M.S.H.) levels were found to be increased in parkinsonism, especially when the disease was bilateral. This explains the seborrhœa of parkinsonism. The defect in M.S.H. secretion is likely to be part of a widespread neuroendocrine abnormality in parkinsonism.
S, Shuster   +5 more
exaly   +11 more sources

Melanocyte-Stimulating Hormone and Adrenocorticotrophic Hormone

New England Journal of Medicine, 1964
HYPERPIGMENTATION in patients with adrenocortical insufficiency or some kinds of pituitary tumors is produced by increased release from the pituitary gland of peptide hormones that cause melanocytes to darken.1 2 3 These peptides are the melanocyte-stimulating hormones (alpha and beta MSH) and adrenocorticotrophin (ACTH). The background of this subject
A B, LERNER, J S, MCGUIRE
openaire   +4 more sources

Hormone-Replacement Therapy for Melanocyte-Stimulating Hormone Deficiency

New England Journal of Medicine, 2016
The first law of endocrine disease treatment is that an absent hormone should be replaced. As they report in this issue of the Journal, Kuhnen et al.1 successfully applied this principle to two adult patients with genetic proopiomelanocortin deficiency, and both patients had impressive hunger reduction and weight loss as well as improved insulin ...
Marc L Reitman
openaire   +4 more sources

Behavioral effects of melanocyte stimulating hormone

Neuroscience & Biobehavioral Reviews, 1980
Abstract Consideration of the isolation, structure, localization, and biological actions of melanocyte stimulating hormone are followed by a review of its behavioral effects. Evidence pertaining to various hypotheses offered in explanation of these behavioral effects is examined and evaluated.
G J, LaHoste   +3 more
openaire   +2 more sources

α-Melanocyte-stimulating hormone and behavior

Neuroscience & Biobehavioral Reviews, 1982
Melanocyte-stimulating hormone (MSH) has putative adaptive significance in all forms of species where it is present. In mammals the polypeptide chain influences learning, memory and attention. Chemically MSH shares the first 13 (alpha-MSH) or the first 18 or 22 (beta-MSH) amino acids with adrenocorticotropic hormone (ACTH), even though the mechanisms ...
P C, Datta, M G, King
openaire   +2 more sources

Natriuretic Properties of Melanocyte-Stimulating Hormones

Journal of Cardiovascular Pharmacology, 1993
Proopiomelanocortin (POMC) is a protein that contains the amino acid sequences of numerous peptide hormones, including the melanocyte-stimulating hormones (MSH). MSH peptides of alpha, beta, and gamma primary structure are present in plasma, and all exhibit natriuretic activity.
J P, Valentin   +2 more
openaire   +2 more sources

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