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Melanocortins, which are involved in melanocyte pigmentation control and glucocorticoid stimulation, have functional roles in various physiological mechanisms and have been shown to participate in higher cortical functions.
Sung-Kil Lim +2 more
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MELANOCYTE-STIMULATING HORMONE AND PARKINSONISM
The Lancet, 1973Abstract Circulating b-melanocyte-stimulating-hormone (β-M.S.H.) levels were found to be increased in parkinsonism, especially when the disease was bilateral. This explains the seborrhœa of parkinsonism. The defect in M.S.H. secretion is likely to be part of a widespread neuroendocrine abnormality in parkinsonism.
S, Shuster +5 more
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Annals of the New York Academy of Sciences, 1963
Teh H Lee, Aaron B Lerner, A B Lerner
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Teh H Lee, Aaron B Lerner, A B Lerner
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Melanocyte-Stimulating Hormone and Adrenocorticotrophic Hormone
New England Journal of Medicine, 1964HYPERPIGMENTATION in patients with adrenocortical insufficiency or some kinds of pituitary tumors is produced by increased release from the pituitary gland of peptide hormones that cause melanocytes to darken.1 2 3 These peptides are the melanocyte-stimulating hormones (alpha and beta MSH) and adrenocorticotrophin (ACTH). The background of this subject
A B, LERNER, J S, MCGUIRE
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Adrenocorticotropin and Melanocyte-Stimulating Hormone in the Brain*
Endocrinology, 1979We employed several ACTH immunoassays using antisera with affinities for differing regions of the molecule as well as an ACTH bioassay to further study the distribution and character of ACTH in rat, cat, and monkey brain. Acid extracts of brain tissues were examined for N-terminal and midportion ACTH concentrations and MSH content.
E, Orwoll +3 more
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The aim of this study was to characterize the pituitary-interrenal axis in barfin flounder, a flatfish. Adrenocorticotropic hormone (ACTH) and melanocortin 2 receptor (MC2R) have been shown to be indispensable substances in pituitary and interrenal cells
Takeshi Yamanome +2 more
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Behavioral effects of melanocyte stimulating hormone
Neuroscience & Biobehavioral Reviews, 1980Abstract Consideration of the isolation, structure, localization, and biological actions of melanocyte stimulating hormone are followed by a review of its behavioral effects. Evidence pertaining to various hypotheses offered in explanation of these behavioral effects is examined and evaluated.
G J, LaHoste +3 more
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Natriuretic Properties of Melanocyte-Stimulating Hormones
Journal of Cardiovascular Pharmacology, 1993Proopiomelanocortin (POMC) is a protein that contains the amino acid sequences of numerous peptide hormones, including the melanocyte-stimulating hormones (MSH). MSH peptides of alpha, beta, and gamma primary structure are present in plasma, and all exhibit natriuretic activity.
J P, Valentin +2 more
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A radioimmunoassay for γ-melanocyte stimulating hormone
Life Sciences, 1980A specific radioimmunoassay for ..gamma..-melanocyte stimulating hormone-like peptides was developed. An antiserum raised in rabbit to synthetic bovine ..gamma../sub 3/-MSH, one of the possible ..gamma..-MSH peptides, specifically recognizes the portion between His/sup 5/ and Arg/sup 14/ of ..gamma../sub 3/-MSH without significant cross-reaction with ...
T, Shibasaki, N, Ling, R, Guillemin
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α-Melanocyte-stimulating hormone and behavior
Neuroscience & Biobehavioral Reviews, 1982Melanocyte-stimulating hormone (MSH) has putative adaptive significance in all forms of species where it is present. In mammals the polypeptide chain influences learning, memory and attention. Chemically MSH shares the first 13 (alpha-MSH) or the first 18 or 22 (beta-MSH) amino acids with adrenocorticotropic hormone (ACTH), even though the mechanisms ...
P C, Datta, M G, King
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