Results 221 to 230 of about 35,415 (321)

Hypersomatotropism and Hypercortisolism Caused by a Plurihormonal Pituitary Adenoma in a Dog

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT A 12‐year‐old, male Labrador Retriever was presented because of polyuria, polydipsia, polyphagia, joint pain, and physical features consistent with acromegaly. Circulating insulin‐like growth factor‐1 (IGF‐1) concentration was increased (> 1000 ng/mL; reference interval [RI], 42–449), suggestive of hypersomatotropism.
Elber A. Soler Arias   +3 more
wiley   +1 more source

Hyperphagia in Bardet–Biedl syndrome: Pathophysiology, burden, and management

open access: yesObesity Reviews, Volume 26, Issue 7, July 2025.
Summary Bardet–Biedl syndrome (BBS) is a rare, genetically heterogeneous, and highly pleiotropic autosomal recessive ciliopathy. Patients typically present with early loss of vision, hyperphagia, severe obesity, learning difficulties, and renal dysfunction. In patients with BBS, dysfunction of the immotile primary cilia in the hypothalamic melanocortin‐
Philip L. Beales   +7 more
wiley   +1 more source

Editorial: Advances and novel intervention in photodermatology. [PDF]

open access: yesFront Med (Lausanne)
Sun Y, Du Y, Hu Y, Li L, Zheng Y.
europepmc   +1 more source

Disruption of mc1r Disturbs Skin Pigmentation in Xenopus tropicalis

open access: yesPigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.
ABSTRACT The melanocortin 1 receptor (MC1R) is well‐established as a pivotal regulator of pigmentation in various species. Despite a wealth of research focused on mammals and fish, the role of Mc1r in amphibians has remained largely unexplored. This study was designed to elucidate the contribution of Mc1r in Xenopus tropicalis.
Lanxin Li   +3 more
wiley   +1 more source

Transcriptional reprogramming triggered by neonatal UV radiation or Lkb1 loss prevents BRAF<sup>V600E</sup>-induced growth arrest in melanocytes. [PDF]

open access: yesOncogene
McGrail K   +10 more
europepmc   +1 more source

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