Results 291 to 300 of about 85,786 (342)

Metabolic anomalies in vitiligo: a new frontier for drug repurposing strategies. [PDF]

Front Pharmacol
Paganelli A, Papaccio F, Picardo M, Bellei B.   +3 more
europepmc   +1 more source

Identification of a Distal Enhancer That Regulates TGF‐β–Induced SNAI1 Expression

Cancer Science, Volume 116, Issue 8, Page 2137-2149, August 2025.
In TGF‐β–stimulated cells, the activated Smad complex composed of Smad3 and Smad4 associates with the distal super enhancer region 2 (DSE2) and enhances its interaction with the SNAI1 proximal promoter, thus inducing SNAI1 expression. RREB1 regulates the basal activity of the enhancer but not its inducibility by TGF‐β.
Hao Fu, Yuka Itoh, Tomoe Sawaguchi, Shigeo Otake, Chiho Omata, Masao Saitoh, Keiji Miyazawa   +6 more
wiley   +1 more source

The Melanophilin knockout chicken, as a new alopecia animal model. [PDF]

Poult Sci
Kim DH, Lee J, Choi W, Lee K.
europepmc   +1 more source

Large Congenital Melanocytic Nevus With LMNA::NTRK1 Fusion: Expanding Targeted Therapy Options for Congenital Nevi and Melanoma

Journal of Cutaneous Pathology, Volume 52, Issue 8, Page 523-527, August 2025.
ABSTRACT Large congenital melanocytic nevi/nevus (LCMN) are caused by genetic events that activate the mitogen‐activated protein kinase (MAPK) and extracellular signal‐regulated kinase (ERK) pathway. Individuals with LCMN are prone to developing aggressive melanomas during childhood.
Akanksha Nagarkar, Jackson Turbeville, Molly A. Hinshaw, Philip E. LeBoit, Jeffrey Gagan, Mark Raffeld, Kenneth Aldape, Niharika Shah, Frederic G. Barr, Liqiang Xi, Ina Lee, Christina K. Ferrone, Svetlana D. Pack, Rosandra Kaplan, Mary Frances Wedekind Malone, Marielle Yohe, Michael R. Sargen   +16 more
wiley   +1 more source

Effect of Fibroblast Growth Factor-2 on Melanocyte Proliferation in Tissue-Engineered Skin Substitutes. [PDF]

Int J Mol Sci
Ferland K, Magne B, De Koninck H, Barbier MA, Larouche D, Germain L.   +5 more
europepmc   +1 more source

Delineating Tissue‐Specific Cell Identity of Oral Mucosa in Humans and Mice From a Single‐Cell Perspective

Journal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT The oral mucosa exhibits superior healing and minimal scarring. Although mouse models are widely used to study wound healing and various diseases, their translational relevance remains unclear. Here, we performed a comparative single‐cell transcriptomic analysis of human and mouse oral mucosa to identify both shared and species‐specific ...
Huanyu Luo, Xiaoyi Yu, Hongchen Sun, Zhengwen An   +3 more
wiley   +1 more source

Amelanotic Melanoma in Oculocutaneous Albinism: Clinical Presentation and Diagnostic Pitfalls with Dermoscopic-Histopathological Correlation. [PDF]

Dermatol Pract Concept
Gioco D, Girolami I, Inchaurraga MAG, Massone C, Sola S, Pizzichetta MA.   +5 more
europepmc   +1 more source

Aging of the Human Lip: Current Knowledge and Clinical Implications

Journal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Comprehensive exploration of lip aging remains limited due to anatomical complexity of the structure, with current investigations predominantly focusing on aspects such as dryness management, cheilitis prevention and treatment, and surgical lifts.
Fanghui Sun, Yue Liu, Tao Zhang
wiley   +1 more source

Uncovering minimal pathways in melanoma initiation. [PDF]

Nat Commun
Xiao H, Shiu J, Chen CF, Wu J, Zhou P, Telang SS, Ruiz-Vega R, Edwards RA, Nie Q, Lander AD, Ganesan AK.   +10 more
europepmc   +1 more source