Results 221 to 230 of about 11,542 (237)

Illumination of the Melanopsin Signaling Pathway

Science, 2005
In mammals, a small population of intrinsically photosensitive retinal ganglion cells (ipRGCs) plays a key role in the regulation of nonvisual photic responses, such as behavioral responses to light, pineal melatonin synthesis, pupillary light reflex, and sleep latency.
Satchidananda, Panda, Surendra K, Nayak, Brice, Campo, John R, Walker, John B, Hogenesch, Tim, Jegla   +5 more
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Melanopsin and other novel mammalian opsins

Experimental Eye Research, 2005
Within the past decade, several non-canonical opsins have been identified in mammals. These include RGR, peropsin, melanopsin, encephalopsin, and neuropsin. Although all are expressed in the eye, it is likely that they serve to mediate non-visual effects of light on physiology.
Tida, Kumbalasiri, Ignacio, Provencio
openaire   +2 more sources

Can We See with Melanopsin?

Annual Review of Vision Science, 2020
A small fraction of mammalian retinal ganglion cells are directly photoreceptive thanks to their expression of the photopigment melanopsin. These intrinsically photosensitive retinal ganglion cells (ipRGCs) have well-established roles in a variety of reflex responses to changes in ambient light intensity, including circadian photoentrainment.
Lucas, Robert J, Allen, Annette E, Milosavljevic, Nina, Storchi, Riccardo, Woelders, Tom   +4 more
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Melanopsin in the Circadian Timing System

Journal of Molecular Neuroscience, 2003
In mammals, circadian rhythms are generated by a light-entrainable oscillator located in the hypothalamic suprachiasmatic nucleus (SCN). Light signals reach the SCN via a dedicated retinal pathway, the retinohypothalamic tract (RHT). One question that continues to elude scientists is whether the circadian system has its own dedicated photoreceptor or ...
Christian, Beaulé, Barry, Robinson, Elaine Waddington, Lamont, Shimon, Amir   +3 more
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Does Melanopsin Bistability Have Physiological Consequences?

Journal of Biological Rhythms, 2008
Recent publications in the Journal of Biological Rhythms have focused on the hypothesis that the property of melanopsin bistability is functionally translated to in vivo mammalian physiology. Physiological consequences of photopigment bistability likely can be inferred from the more extensive invertebrate literature.
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Melanopsin, Ganglion-Cell Photoreceptors, and Mammalian Photoentrainment

Journal of Biological Rhythms, 2003
An understanding of the retinal mechanisms in mammalian photoentrainment will greatly facilitate optimization of the wavelength, intensity, and duration of phototherapeutic treatments designed to phase shift endogenous biological rhythms. A small population of widely dispersed retinal ganglion cells projecting to the suprachiasmatic nucleus in the ...
Mark D, Rollag, David M, Berson, Ignacio, Provencio   +2 more
openaire   +2 more sources

Melanopsin: photoreceptors, physiology and potential

Current Opinion in Physiology, 2018
The discovery of melanopsin-expressing photosensitive retinal ganglion cells (pRGCs) has led to a fundamental change in our understanding of retinal light detection. pRGCs perform a broad range of non-visual functions — most notably mediating circadian entrainment to the environmental light/dark cycle.
Palumaa, T, Gilhooley, M, Jagannath, A, Hankins, M, Hughes, S, Peirson, S   +5 more
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[Pupil and melanopsin photoreception].

Nippon Ganka Gakkai zasshi, 2013
The iris is the most anterior portion of the uveal tract. The pupil is round opening near the center of the iris; it is displaced slightly downward and nasally with respect to the center of the cornea. The mammalian iris sphincter is considered to be innervated by cholinergic, and the dilator muscle by adrenergic excitatory nerve fibers, and both ...
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Responding to Light with Melanopsin

Science's STKE, 2005
Certain mammalian retinal ganglion cells that express melanopsin act as photoreceptors that regulate circadian and pupillary responses. Although melanopsin is required for the photosensitivity of these cells, and has been proposed to act as a photopigment, its exact function has been uncertain. Two groups, Qiu et al
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Melanopsin phototransduction

2012
Steven Hughes, Mark W. Hankins, Russell G. Foster, Stuart N. Peirson   +3 more
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