Results 91 to 100 of about 3,657 (172)

In-silico predicted mouse melanopsins with blue spectral shifts deliver efficient subcellular signaling

Cell Communication and Signaling
Melanopsin is a photopigment belonging to the G Protein-Coupled Receptor (GPCR) family expressed in a subset of intrinsically photosensitive retinal ganglion cells (ipRGCs) and responsible for a variety of processes.
Dhanushan Wijayaratna, Filippo Sacchetta, Laura Pedraza-González, Francesca Fanelli, Tomohiro Sugihara, Mitsumasa Koyanagi, Senuri Piyawardana, Kiran Ghotra, Waruna Thotamune, Akihisa Terakita, Massimo Olivucci, Ajith Karunarathne   +11 more
doaj   +1 more source

Rods contribute to the light-induced phase shift of the retinal clock in mammals.

PLoS Biology, 2019
While rods, cones, and intrinsically photosensitive melanopsin-containing ganglion cells (ipRGCs) all drive light entrainment of the master circadian pacemaker of the suprachiasmatic nucleus, recent studies have proposed that entrainment of the mouse ...
Hugo Calligaro, Christine Coutanson, Raymond P Najjar, Nadia Mazzaro, Howard M Cooper, Nasser Haddjeri, Marie-Paule Felder-Schmittbuhl, Ouria Dkhissi-Benyahya   +7 more
doaj   +1 more source

Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina

Scientific Reports, 2017
In the vertebrate retina, dopamine is synthesized and released by a specialized type of amacrine cell, the dopaminergic amacrine cell (DAC). DAC activity is stimulated by rods, cones, and melanopsin-expressing intrinsically photosensitive retinal ...
Xiwu Zhao, Kwoon Y. Wong, Dao-Qi Zhang
doaj   +1 more source

Rhodopsin and Melanopsin Contributions to the Early Redilation Phase of the Post-Illumination Pupil Response (PIPR).

PLoS ONE, 2016
Melanopsin expressing intrinsically photosensitive Retinal Ganglion Cells (ipRGCs) entirely control the post-illumination pupil response (PIPR) from 6 s post-stimulus to the plateau during redilation after light offset.
Prakash Adhikari, Beatrix Feigl, Andrew J Zele   +2 more
doaj   +1 more source

Blue light stimulation of the blind spot in human: from melanopsin to clinically relevant biomarkers of myopia

Bioelectronic Medicine
The protective effects of time spent outdoors emphasize the major role of daylight in myopia. Based on the pathophysiology of myopia, the impact of blue light stimulation on the signaling cascade, from melanopsin at the blind spot to clinically relevant ...
Ana Amorim-de-Sousa, Ranjay Chakraborty, Michael J. Collins, Paulo Fernandes, José González‑Méijome, Jens Hannibal, Hosein Hoseini-Yazdi, Scott A. Read, Jens Ellrich, Tim Schilling   +9 more
doaj   +1 more source

[Phototransduction mediated by melanopsin in intrinsically photosensitive retinal ganglion cells].

Gaceta medica de Mexico, 2016
Melanopsin is the most recent photopigment described. As all the other opsins, it attaches in the retina as chromophore. Its amino acid sequence resembles more invertebrate opsins than those of vertebrates. The signal transduction pathway of opsins in vertebrates is based on the coupling to the G protein transducin, triggering a signaling cascade that ...
Carlos Augusto, Domínguez-Solís, Jorge Alberto, Pérez-León   +1 more
openaire   +1 more source

Not just a covariate: circadian photoreception varies by age and sex. [PDF]

Sleep
Wescott D.
europepmc   +1 more source

Functional methods for evaluating the efficacy of retinal optogenetic therapy for vision restoration. [PDF]

Front Neurosci
Borchert GA, Shamsnajafabadi H, Xue K, MacLaren RE, De Silva SR, Cehajic-Kapetanovic J.   +5 more
europepmc   +1 more source

Neuropsin-expressing cells in the retina affect melanopsin expression and response to light in mice. [PDF]

Sci Rep
Calligaro H, Khov B, Kim KY, Le H, Ellisman M, Panda S.   +5 more
europepmc   +1 more source

The role of circadian rhythms in the pathogenesis of myopia. [PDF]

Front Physiol
Zhang N, Han G, Hao R.
europepmc   +1 more source