Results 121 to 130 of about 7,378 (211)

Hyperpolarization-activated current (I(h)) in ganglion-cell photoreceptors.

open access: yesPLoS ONE, 2010
Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin and serve as the primary retinal drivers of non-image-forming visual functions such as circadian photoentrainment, the pupillary light reflex, and ...
Matthew J Van Hook, David M Berson
doaj   +1 more source

Differential monocular vs. binocular pupil responses from melanopsin-based photoreception in patients with anterior ischemic optic neuropathy. [PDF]

open access: yes, 2015
We examined the effect of anterior ischemic optic neuropathy (AION) on the activity of intrinsically photosensitive retinal ganglion cells (ipRGCs) using the pupil as proxy.
Crippa, S.V., Kawasaki, A., Tsika, C.
core   +1 more source

Evolution of mammalian Opn5 as a specialized UV-absorbing pigment by a single amino acid mutation. [PDF]

open access: yes, 2014
Opn5 is one of the recently identified opsin groups that is responsible for nonvisual photoreception in animals. We previously showed that a chicken homolog of mammalian Opn5 (Opn5m) is a Gi-coupled UV sensor having molecular properties typical of ...
Fujita, Hirofumi   +11 more
core   +1 more source

Unexpected diversity and photoperiod dependence of the zebrafish melanopsin system.

open access: yesPLoS ONE, 2011
Animals have evolved specialized photoreceptors in the retina and in extraocular tissues that allow them to measure light changes in their environment.
Vanessa Matos-Cruz   +5 more
doaj   +1 more source

β-Arrestin-dependent deactivation of mouse melanopsin.

open access: yesPLoS ONE, 2014
In mammals, the expression of the unusual visual pigment, melanopsin, is restricted to a small subset of intrinsically photosensitive retinal ganglion cells (ipRGCs), whose signaling regulate numerous non-visual functions including sleep, circadian ...
Evan G Cameron, Phyllis R Robinson
doaj   +1 more source

Impaired Circadian Photoentrainment in Opn5-Null Mice

open access: yesiScience, 2018
Summary: The master circadian pacemaker in mammals resides in the hypothalamic suprachiasmatic nuclei (SCN) and is synchronized to ambient light/dark cycles (i.e., photoentrainment). Melanopsin (Opn4) and classical rod-cone photoreceptors are believed to
Wataru Ota   +3 more
doaj   +1 more source

Blue light as a drug? [PDF]

open access: yes, 2015
Treballs Finals de Grau de Farmàcia, Facultat de Farmàcia, Universitat de Barcelona, 2015. Tutora: Trinitat Cambras Riu.[eng] This Final Project is based on bibliographic research and integration of recent scientific articles that contain information ...
Ferré Ferré, Aileen
core  

Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells

open access: yesVision Research, 2007
Melanopsin, a novel photopigment, has recently been localized to a population of retinal ganglion cells that display inherent photosensitivity. During continuous light and following light offset, primates are known to exhibit sustained pupilloconstriction responses that resemble closely the photoresponses of intrinsically-photoreceptive ganglion cells.
Gamlin, Paul D.R.   +5 more
openaire   +2 more sources

In-silico predicted mouse melanopsins with blue spectral shifts deliver efficient subcellular signaling

open access: yesCell Communication and Signaling
Melanopsin is a photopigment belonging to the G Protein-Coupled Receptor (GPCR) family expressed in a subset of intrinsically photosensitive retinal ganglion cells (ipRGCs) and responsible for a variety of processes.
Dhanushan Wijayaratna   +11 more
doaj   +1 more source

Rods contribute to the light-induced phase shift of the retinal clock in mammals.

open access: yesPLoS Biology, 2019
While rods, cones, and intrinsically photosensitive melanopsin-containing ganglion cells (ipRGCs) all drive light entrainment of the master circadian pacemaker of the suprachiasmatic nucleus, recent studies have proposed that entrainment of the mouse ...
Hugo Calligaro   +7 more
doaj   +1 more source

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