Results 1 to 10 of about 12,239 (244)

The clinical spectrum of MELAS and associated disorders across ages: a retrospective cohort study

Frontiers in Neurology, 2023
ObjectiveMitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a severe multisystemic disease, although some have a milder phenotype.
Jay Mandrekar, Mandrekar Jay
exaly   +3 more sources

Impaired respiratory function in MELAS‐induced pluripotent stem cells with high heteroplasmy levels

FEBS Open Bio, 2015
Mitochondrial diseases are heterogeneous disorders, caused by mitochondrial dysfunction. Mitochondria are not regulated solely by nuclear genomic DNA but by mitochondrial DNA.
Shinsuke Yuasa, Hisayuki Hashimoto, Yu-Ichi Gotō   +2 more
exaly   +2 more sources

MELAS syndrome complicated by anti-GFAP autoantibody positivity: a case report and literature review [PDF]

BMC Neurology
Background Autoimmune abnormalities have been reported in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, but anti-glial fibrillary acidic protein (GFAP) antibody positivity in both serum and cerebrospinal ...
Jun Shu, Yiping Zhou, Ziwei Xu, Wenshi Wei, Lirong Zhao, Jie Chang   +5 more
doaj   +2 more sources

Migratory vasodilatation of cerebral arteries in MELAS episodes: a case report and literature review [PDF]

Frontiers in Immunology
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is the commonest inherited mitochondrial disorder. Dilation of the major cerebral arteries is seldom mentioned in MELAS because magnetic resonance angiography (MRA ...
Ying Luo, Quanhong Chu, Quanhong Chu, Taochun Yu, Xiaoqing Lu, Xiaoqing Lu, Yanmei Wang, Yanmei Wang, Jie Li, Jie Li, Lingfeng Wu, Lingfeng Wu, Yaoyao Shen, Yaoyao Shen   +13 more
doaj   +2 more sources

Dynamic reconfiguration and transition of whole-brain networks in patients with MELAS revealed by a hidden Markov model [PDF]

Frontiers in Neurology
ObjectivesMitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is a rare maternally inherited disease. The neuropathologic mechanisms and neural network alterations underlying stroke-like episodes (SLEs), a recurrent ...
Qingyun Yu, Qingyun Yu, Rong Wang, Chong Sun, Bin Hu, Xueling Liu, Liqin Yang, Jie Lin, Daoying Geng, Daoying Geng, Daoying Geng, Yuxin Li   +11 more
doaj   +2 more sources

Case Report: Simultaneous pancreas–kidney transplantation in MELAS: first reported case with 5-year follow-up [PDF]

Frontiers in Transplantation
BackgroundMitochondrial encephalomyopathy with lactic acidosis, and stroke-like episodes (MELAS) is a rare mitochondrial DNA disorder that, in severe cases, can result in insulin-dependent diabetes and end-stage renal disease (ESRD).
Vera Nilsén, Vera Nilsén, Julia Bojstedt, Johan Nordström, Johan Nordström   +4 more
doaj   +2 more sources

Microhemorrhages in MELAS Lesions: A Case Report

Journal of the Belgian Society of Radiology, 2022
Introduction: Microhemorrhages have not been described in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) on magnetic resonance imaging (MRI).
Evelien Martens, Jelle Demeestere, Benjamin Verhaaren   +2 more
doaj   +1 more source

A different pattern of clinical, muscle pathology and brain MRI findings in MELAS with mt‐ND variants

Annals of Clinical and Translational Neurology, 2023
Objective To explore the clinical characteristics of mitochondrial encephalomyopathy, lactic acidosis, and stroke‐like episodes (MELAS) caused by mitochondrial DNA‐encoded complex I subunit (mt‐ND) variants.
Wei Wang, Yuying Zhao, Xuebi Xu, Xiaotian Ma, Yuan Sun, Yan Lin, Ying Zhao, Zhihong Xu, Jiayin Wang, Hong Ren, Bin Wang, Dandan Zhao, Dongdong Wang, Fuchen Liu, Wei Li, Chuanzhu Yan, Kunqian Ji   +16 more
doaj   +1 more source

Total intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case report- [PDF]

Korean Journal of Anesthesiology, 2010
A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction.
Jin Suk Park, Chong Wha Baek, Hyun Kang, Su Man Cha, Jung Won Park, Yong Hun Jung, Young-Cheol Woo   +6 more
doaj   +1 more source

Neo-Riemannian Theory and the Melakarta [PDF]

Analytical Approaches to World Music, 2023
Utilizing a Neo-Riemannian lens and pitch-class set analysis, this article investigates the Melakarta—a South Indian classification system for ragas. There are two main goals.
John King
doaj