Results 1 to 10 of about 46,096 (249)

MRI Features of Stroke-Like Episodes in Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-Like Episodes [PDF]

Frontiers in Neurology, 2022
Mitochondrial myopathy encephalopathy lactic acidosis and stroke-like episodes (MELAS) is an important cause of stroke-mimicking diseases that predominantly affect patients before 40 years of age. MELAS results from gene mutations in either mitochondrial
Weiqin Cheng, Yuting Zhang, Ling He
doaj   +7 more sources

Stroke-like Episodes in Inherited Neurometabolic Disorders [PDF]

Metabolites, 2022
Stroke-like episodes (SLEs) are significant clinical manifestations of metabolic disorders affecting the central nervous system. Morphological equivalents presented in neuroimaging procedures are described as stroke-like lesions (SLLs).
Natalia Będkowska, Aneta Zontek, Justyna Paprocka   +2 more
doaj   +4 more sources

Mitochondrial stroke-like episodes: The search for new therapies

Pharmacological Research, 2022
A mitochondrial stroke-like event is an evolving subacute neurological syndrome linked to seizure activity and focal metabolic brain derangement in a genetically determined mitochondrial disorder.
Daniele Orsucci, Elena Caldarazzo Ienco, Vincenzo Montano, Gabriele Siciliano, Michelangelo Mancuso   +4 more
doaj   +6 more sources

Stroke-Like episodes and epilepsy in a patient with COQ8A-Related coenzyme Q10 deficiency [PDF]

Annals of Indian Academy of Neurology, 2023
Coenzyme q10 (CoQ10) deficiency is an extremely uncommon disease that has very rarely been reported in adulthood. This case describes an elderly male with ataxia since adolescence, and visual disturbance since 40, presenting with recurrent episodes of ...
Rithvik Ramesh, Sundar Hariharan, Latha Sundar   +2 more
doaj   +2 more sources

Systemic Sarcoidosis Presenting with Headache and Stroke-Like Episodes [PDF]

Case Reports in Immunology, 2015
Sarcoidosis is a multisystem granulomatous disorder. Neurological manifestations as a presenting symptom are relatively rare. A 26-year-old male presented with a five-week history of headache suggestive of raised intracranial pressure.
J. Campbell, R. Kee, D. Bhattacharya, P. Flynn, M. McCarron, A. Fulton   +5 more
doaj   +5 more sources

Clinicoradiologic Criteria for the Diagnosis of Stroke-like Episodes in MELAS. [PDF]

Neurol Genet, 2023
Stroke-like episodes (SLEs) in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome are often misdiagnosed as acute ischemic stroke (AIS). We aimed to determine unique clinical and neuroimaging features for SLEs and formulate diagnostic criteria.We retrospectively identified patients with MELAS ...
Khasminsky V, Auriel E, Luckman J, Eliahou R, Inbar E, Pardo K, Landau Y, Barnea R, Mermelstein M, Shelly S, Naftali J, Peretz S.   +11 more
europepmc   +3 more sources

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes with coexisting nemaline myopathy: a case report [PDF]

Journal of Medical Case Reports
Background Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes and nemaline myopathy are two rare genetic conditions. We report the first case reported in world literature with coexistence of both these rare disorders.
Kawmadi Gunawardena, Somasundaram Praveenan, Vajira H. W. Dissanayake, Pyara Ratnayake   +3 more
doaj   +2 more sources

Melas, Stroke-Like Episodes and Ketogenic Diet

Pediatric Neurology Briefs, 2014
Investigators at University of Toronto and McMaster University, Canada, report a 22-year-old woman with multiple episodes of status epilepticus and migratory cortical stroke-like lesions.
J Gordon Millichap, John J Millichap
doaj   +4 more sources

Forecasting stroke-like episodes and outcomes in mitochondrial disease. [PDF]

Brain, 2022
AbstractIn this retrospective, multicentre, observational cohort study, we sought to determine the clinical, radiological, EEG, genetics and neuropathological characteristics of mitochondrial stroke-like episodes and to identify associated risk predictors.Between January 1998 and June 2018, we identified 111 patients with genetically determined ...
Ng YS, Lax NZ, Blain AP, Erskine D, Baker MR, Polvikoski T, Thomas RH, Morris CM, Lai M, Whittaker RG, Gebbels A, Winder A, Hall J, Feeney C, Farrugia ME, Hirst C, Roberts M, Lawthom C, Chrysostomou A, Murphy K, Baird T, Maddison P, Duncan C, Poulton J, Nesbitt V, Hanna MG, Pitceathly RDS, Taylor RW, Blakely EL, Schaefer AM, Turnbull DM, McFarland R, Gorman GS.   +32 more
europepmc   +6 more sources

Diabetes Ketoacidosis and Recurrent Childhood Stroke-like Episodes

Acta Neurologica Taiwanica
A 13-year and 4-month-old girl was brought to the emergency department due to fever, dizziness,vomiting, and blurred vision. Laboratory data revealed hyperglycemia with an HbA1C of 7.3 percent, ketonuria, and lactic acidosis. The initial impression was diabetic ketoacidosis.
Ren-Chuan Liu, Ji-Nan Sheu, Chin-San Liu, Jeng-Dau Tsai   +3 more
doaj   +3 more sources