MRI Features of Stroke-Like Episodes in Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-Like Episodes. [PDF]
Front Neurol, 2022 Mitochondrial myopathy encephalopathy lactic acidosis and stroke-like episodes (MELAS) is an important cause of stroke-mimicking diseases that predominantly affect patients before 40 years of age. MELAS results from gene mutations in either mitochondrial
Cheng W, Zhang Y, He L.
europepmc +7 more sources
Stroke-like Episodes in Inherited Neurometabolic Disorders. [PDF]
Metabolites, 2022 Stroke-like episodes (SLEs) are significant clinical manifestations of metabolic disorders affecting the central nervous system. Morphological equivalents presented in neuroimaging procedures are described as stroke-like lesions (SLLs).
Będkowska N, Zontek A, Paprocka J.
europepmc +4 more sources
Mitochondrial Stroke-Like Episodes: The Search for New Therapies
Pharmacological Research, 2022 A mitochondrial stroke-like event is an evolving subacute neurological syndrome linked to seizure activity and focal metabolic brain derangement in a genetically determined mitochondrial disorder.
Gabriele Siciliano +2 more
exaly +6 more sources
Stroke-Like Episodes and Epilepsy in a Patient with COQ8A-Related Coenzyme Q10 Deficiency. [PDF]
Ann Indian Acad Neurol, 2023 Coenzyme q10 (CoQ10) deficiency is an extremely uncommon disease that has very rarely been reported in adulthood. This case describes an elderly male with ataxia since adolescence, and visual disturbance since 40, presenting with recurrent episodes of ...
Ramesh R, Hariharan S, Sundar L.
europepmc +2 more sources
Systemic Sarcoidosis Presenting with Headache and Stroke-Like Episodes [PDF]
Case Reports in Immunology, 2015 Sarcoidosis is a multisystem granulomatous disorder. Neurological manifestations as a presenting symptom are relatively rare. A 26-year-old male presented with a five-week history of headache suggestive of raised intracranial pressure.
J. Campbell +5 more
doaj +5 more sources
Melas, Stroke-Like Episodes and Ketogenic Diet
Pediatric Neurology Briefs, 2014 Investigators at University of Toronto and McMaster University, Canada, report a 22-year-old woman with multiple episodes of status epilepticus and migratory cortical stroke-like lesions.
J Gordon Millichap, John J Millichap
doaj +4 more sources
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes with coexisting nemaline myopathy: a case report. [PDF]
J Med Case RepBackground Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes and nemaline myopathy are two rare genetic conditions. We report the first case reported in world literature with coexistence of both these rare disorders.
Gunawardena K +3 more
europepmc +2 more sources
Profiles of paediatric patients experiencing stroke-like episodes associated with mitochondrial disease. [PDF]
Front NeurolIntroductionStroke-like episodes (SLE) are defined as events characterized by the sudden onset of neurological symptoms with clinical manifestations similar to those of a stroke.
Molla GK +17 more
europepmc +2 more sources
Antiepileptics and NO-precursors may be beneficial for stroke-like episodes
eNeurologicalSci, 2019 Pathogenesis and management of stroke-like episodes in mitochondrial disorders is under debate and no consensus has been reached thus far how this phenomenon should be managed. Frequently applied are nitric oxide (NO) precursors but a well-designed study
Josef Finsterer
doaj +3 more sources
Gastrointestinal Complications of Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS) Syndrome Managed By Parenteral Nutrition. [PDF]
Eur J Case Rep Intern MedMELAS – an acronym for mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes – is a multiorgan disease caused by a mutation in mitochondrial DNA (mtDNA).
Horná S +6 more
europepmc +2 more sources