Diabetes Ketoacidosis and Recurrent Childhood Stroke-like Episodes
A 13-year and 4-month-old girl was brought to the emergency department due to fever, dizziness,vomiting, and blurred vision. Laboratory data revealed hyperglycemia with an HbA1C of 7.3 percent, ketonuria, and lactic acidosis. The initial impression was diabetic ketoacidosis.
Ren-Chuan Liu +3 more
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Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a maternally inherited mitochondrial disorder that is most commonly caused by the m.
Delia Gagliardi +21 more
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Antiepileptics and NO-precursors may be beneficial for stroke-like episodes
Pathogenesis and management of stroke-like episodes in mitochondrial disorders is under debate and no consensus has been reached thus far how this phenomenon should be managed. Frequently applied are nitric oxide (NO) precursors but a well-designed study
Josef Finsterer
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Profiles of paediatric patients experiencing stroke-like episodes associated with mitochondrial disease [PDF]
IntroductionStroke-like episodes (SLE) are defined as events characterized by the sudden onset of neurological symptoms with clinical manifestations similar to those of a stroke.
Gülhan Karakaya Molla +18 more
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Gao-Li Fang,1 Yang Zheng,2 Yin-Xi Zhang2 1Department of Neurology, Hangzhou Red Cross Hospital, Hangzhou, China; 2Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China Abstract: Few cases of ...
Fang GL, Zheng Y, Zhang YX
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Gastrointestinal complications of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome managed by parenteral nutrition [PDF]
MELAS – an acronym for mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes – is a multiorgan disease caused by a mutation in mitochondrial DNA (mtDNA).
Simona Horná +6 more
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Outcomes misaligned in mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS): implications for trial design. [PDF]
\ua9 The Author(s) 2025. Published by Oxford University Press on behalf of the Guarantors of Brain. The m.3243A>G variant in the MT-TL1 gene is the most prevalent pathogenic variant in mitochondrial DNA in adults, associated with a wide clinical ...
Stefanetti RJ +6 more
europepmc +6 more sources
Uveitis and Retinal Vasculitis—Harbingers of Neuro-Behcet’s Disease: A Case Report [PDF]
We report this case of Neuro-Behcet’s disease who initially had recurrent episodes of uveitis over a period of 14 years and was under ophthalmological follow-up. Recently, she developed retinal vasculitis and multiple stroke-like episodes.
Pramod Kumar Samala +6 more
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Diagnosis and Management of Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes Syndrome [PDF]
Ji-Hoon Na, Young-Mock Lee
exaly +2 more sources
Microhemorrhages in MELAS Lesions: A Case Report
Introduction: Microhemorrhages have not been described in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) on magnetic resonance imaging (MRI).
Evelien Martens +2 more
doaj +1 more source

