Results 51 to 60 of about 14,508 (226)

Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research Directions

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for
Elena Koning, Jérémie Richard, Aaron Keshen   +2 more
wiley   +1 more source

Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus

Epilepsia, EarlyView.
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger, Pilar Bosque‐Varela, Jürgen Steinbacher, Johannes Pfaff, Eugen Trinka, Giorgi Kuchukhidze   +5 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Impaired Hearing in MELAS

The Journal of International Advanced Otology, 2022
Cite this article as: Finsterer J. Impaired hearing in MELAS. J Int Adv Otol. 2022;18(3):276-277.
openaire   +3 more sources

Metal Accumulation, Liver Histopathology, and Human Health Risk Assessment Across Different Trophic Guilds in a Mining‐Affected Neotropical River

Journal of Applied Toxicology, EarlyView.
ABSTRACT Metal pollution in aquatic environments represents a recurring global concern; however, traditional paradigms often assume linear bioaccumulation patterns that may fail under catastrophic contamination scenarios. This study evaluated metal concentrations in water, sediment, and tissues of 10 fish species from different trophic guilds in the ...
Breno Thuller, Alessandro Loureiro Paschoalini, Fabio Pereira Arantes, Cristiano Schetini de Azevedo, Elizete Rizzo, Nilo Bazzoli   +5 more
wiley   +1 more source

Melas Syndrome

, 1987
Melas syndrome consists of mitochondrial myopathy, encephalopathy, lactic acidosis, and ...
J Gordon Millichap, Millichap, J. Gordon
core   +1 more source

Identification of a Novel Variant in MT-CO3 Causing MELAS

, 2021
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a maternally inherited mitochondrial disease. Most cases of MELAS are caused by the m.3243A > G variant in the MT-TL1 gene encoding tRNALeu((UUR)).
Fang, F., Prokisch, H., Kopajtich, R., Liu, Z., Wang, Z., Wang, J., Xu, M., Elstner, M., Zhaoxia Wang, Robert Kopajtich, Junling Wang, Matthias Elstner, Manting Xu, Xu, Manting;Kopajtich, Robert;Elstner, Matthias;Wang, Zhaoxia;Liu, Zhimei;Wang, Junling;Prokisch, Holger;Fang, Fang, Zhimei Liu, Fang Fang, Holger Prokisch   +16 more
core   +1 more source

Retinal multimodal-imaging and functional tests in a mitochondrial disease with focal and segmental glomerulosclerosis [PDF]

International Journal of Ophthalmology
The phenotypes of the adenine-to-guanine transition at position 3243 of mitochondrial DNA (m.3243A>G) are highly variable, with different symptoms observed in different patients.
Xiao-Hong Liu, Xi Shen, Yi-Sheng Zhong
doaj   +1 more source

MELA/MELA/MELA/MELA! Melán/cho/lía… Dal Bencomune alle Fleurs du Mal

, 2020
Il Deposito di Scienza & Politica è uno spazio in cui pubblicare testi che possono essere dei preprint, dei work in progress o anche dei testi definitivi che si vogliono affidare all’uso comune dei lettori. Si tratta di testi non sottoposti a referaggio, senza nessuna registrazione, che rimangono a disposizione di chi li voglia leggere e utilizzare.
openaire   +2 more sources

MELAS: A Multigenerational Impact of the MTTL1 A3243G MELAS Mutation [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2014
Background:the maternally inherited MTTL1 A3243G mutation in the mitochondrial genome causes MelaS (Mitochondrial encephalopathy lactic acidosis with Stroke-like episodes), a condition that is multisystemic but affects primarily the nervous system. Significant intra-familial variation in phenotype and severity of disease is well recognized.Methods ...
Prasad, M., Narayan, B., Prasad, A. N., Rupar, C. A., Levin, S., Kronick, J., Ramsay, D., Tay, K. Y., Prasad, C.   +8 more
openaire   +3 more sources