MELAS syndrome with rare manifestations misdiagnosed as vasculitis in the absence of lactic acidosis: A case report. [PDF]
Ann Med Surg (Lond), 2022 Introduction The syndrome of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is one of the most common inherited mitochondrial disorders.
Alsultan M +3 more
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MELAS syndrome complicated by anti-GFAP autoantibody positivity: a case report and literature review [PDF]
BMC NeurologyBackground Autoimmune abnormalities have been reported in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, but anti-glial fibrillary acidic protein (GFAP) antibody positivity in both serum and cerebrospinal ...
Jun Shu +5 more
doaj +2 more sources
Gastrointestinal Complications of Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS) Syndrome Managed By Parenteral Nutrition. [PDF]
Eur J Case Rep Intern MedMELAS – an acronym for mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes – is a multiorgan disease caused by a mutation in mitochondrial DNA (mtDNA).
Horná S +6 more
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A Case Report of a Clinically Suspected Diagnosis of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) Syndrome With Cardiac Impairment. [PDF]
CureusThis case report presents a description of a hypertrophic left ventricle with reduced ejection fraction in a man in his mid-twenties with clinical, radiologic, and biochemical features of a rare syndrome called mitochondrial encephalomyopathy, lactic ...
Momoh R, Kollamparambil S.
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Pediatric Neurology Briefs, 1987 Melas syndrome consists of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke.
J Gordon Millichap
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Contribution of nuclear and mitochondrial gene mutations in mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome. [PDF]
J Neurol, 2021 Mitochondrial disorders are clinically complex and have highly variable phenotypes among all inherited disorders. Mutations in mitochon drial DNA (mtDNA) and nuclear genome or both have been reported in mitochondrial diseases suggesting common ...
Chakrabarty S +16 more
europepmc +2 more sources
Comprehensive Diagnostic Criteria for MELAS Syndrome; a Case Study Involving an Elderly Patient With MT-TWm.5541C>T Mutation. [PDF]
Neurologist, 2023 Introduction: The mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a matrilineal hereditary multisystem disease caused by mutations in the mitochondrial DNA.
Wu G +6 more
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MELAS syndrome: an acute stroke-like episode complicated by renal tubular acidosis. [PDF]
BMJ Case Rep, 2021 MELAS, a mitochondrially inherited multisystem disorder, can present with acute stroke-like episodes. The literature thus far supports the use of L-arginine therapy in acute MELAS flares to alleviate and shorten the duration of symptoms. This is the case
Ni Cathain D +3 more
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Acute Cortical Lesions in MELAS Syndrome: Anatomic Distribution, Symmetry, and Evolution. [PDF]
AJNR Am J Neuroradiol, 2020 BACKGROUND AND PURPOSE: Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome is a rare mitochondrial disorder affecting children and young adults.
Bhatia KD +4 more
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Perampanel: A therapeutic alternative in refractory status epilepticus associated with MELAS syndrome [PDF]
Epilepsy and Behavior Case Reports, 2019 To our knowledge, there are no reports of status epilepticus (SE) associated with mitochondrial diseases and treated with perampanel (PER). We present three cases of patients with refractory SE associated with MELAS syndrome who responded favorably to ...
Estevo Santamarina +8 more
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