Results 41 to 50 of about 13,180 (241)

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang   +6 more
wiley   +1 more source

Different therapeutic approaches in melasma: advances and limitations

open access: yesFrontiers in Pharmacology
Melasma is a chronic hyperpigmentation skin disorder that is more common in the female gender. Although melasma is a multifactorial skin disorder, however, sun-exposure and genetic predisposition are considered as the main etiologic factors in melasma ...
Parisa Ghasemiyeh   +6 more
doaj   +1 more source

Perkembangan Penggunaan Kosmeseutikal Herbal Pada Terapi Melasma

open access: yesJurnal Kesehatan Andalas, 2019
Kosmeseutikal herbal merupakan kosmetik topikal yang mengandung bahan alami, berasal dari tanaman. Banyak digunakan sebagai Skin Lightening Agent (SLA) dalam penatalaksanaan melasma.
Mimin Oktaviana, Satya Wydya Yenny
doaj   +1 more source

Unmasking dermoscopic evaluation of melasma: findings of a cross-sectional study in central India

open access: yesClinical Dermatology Review, 2022
Background: There exists a wide range of variations in skin tone around the world, with Asian and Indian subjects showing a greater susceptibility toward pigmentation disorder.
Sahana Sreenath   +4 more
doaj   +1 more source

Hubungan Melasma Dengan Tingkat Kualitas Hidup Pada Wanita [PDF]

open access: yes, 2016
Background: Melasma is hyperpigmentation, generally symmetrical, macular form uneven light brown to dark brown, and most frequently noticed on sun-exposed areas of the face, especially the cheeks, forehead, upper lip, nose, and chin.
Said, Reza Nur
core  

Salicylic acid for the treatment of melasma: new acquisitions for monitoring the clinical improvement. [PDF]

open access: yes, 2013
OBJECTIVE: The Melasma Area and Severity Index (MASI) and the Melasma Severity Score (MSS) are calculated on the basis of only a subjective clinical assessment.
DE VITA, VALERIO   +4 more
core   +1 more source

Bioretinoids from microalgae: Boosting retinol performance and tolerability

open access: yesInternational Journal of Cosmetic Science, Volume 48, Issue 1, Page 146-160, February 2026.
A novel microalgae‐derived bioretinoid (MBR) enhances skin regeneration, improves pigmentation, and reduces signs of ageing more effectively than bakuchiol and comparably to retinol—without the irritation. MBR also synergizes with retinol, boosting hydration and safety. A powerful, gentle alternative for advanced skincare.
Silvia Sánchez‐Díez   +3 more
wiley   +1 more source

Comparative study of melasma in patients before and after treatment based on lipomics

open access: yesLipids in Health and Disease
Background Skin barrier alterations play a crucial function in melasma development. Past researches have demonstrated variations in lipid content between the epidermis of melasma lesions and normal tissues, along with the varied expression of lipid ...
Yuan Zhu   +3 more
doaj   +1 more source

Faktor Risiko Penderita Melasma [PDF]

open access: yes, 2012
Background Melasma is one of the common skin problems, which caused color disturbances in the skin and decrease in confidence of the patients, a generally symmetrical macular hyperpigmentation.
Muslimin, M. (Muslimin)   +1 more
core  

Predictive Factors of Better Patient Satisfaction After Phenol‐Croton Peel: A Retrospective Study of 102 Patients

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Phenol‐croton peels are the gold standard for treating sun‐damaged skin and static wrinkles; their long‐term outcomes and patient satisfaction rates have yet to be thoroughly investigated. Aims To evaluate patient satisfaction and both short‐ and long‐term cutaneous side effects in individuals undergoing phenol‐croton peels ...
Gustavo Carneiro Nogueira   +11 more
wiley   +1 more source

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