Results 211 to 220 of about 227,315 (399)
Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi+6 more
wiley +1 more source
Antigonadal Effects of Melatonin in White-footed Mice (Peromyscus leucopus) [PDF]
Phyllis G. Johnston, Irving Zucker
openalex +1 more source
We studied the impact of circadian misalignment on 238 plasma proteins linked to cardiovascular physiology. We identified 42 proteins with altered abundance, five proteins regulated by the circadian clock, and changes in many proteins in the coagulation pathway.
Andrew W. McHill+3 more
wiley +1 more source
How does melatonin control seasonal reproductive cycles 7 [PDF]
Joséphine Arendt+4 more
openalex +1 more source
Medication‐resistant epilepsy is associated with a unique gut microbiota signature
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva+14 more
wiley +1 more source
Plasma and Pineal Melatonin Levels in Female Ferrets Housed Under Long or Short Photoperiods [PDF]
Michael J. Baum+3 more
openalex +1 more source
In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik+5 more
wiley +1 more source
Diagnostic and clinical implications of plasma and salivary melatonin assay. [PDF]
A Miles+3 more
openalex +1 more source