Results 241 to 250 of about 92,984 (317)

Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao   +12 more
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza   +4 more
wiley   +1 more source

Melatonin in Dermatology

open access: yesIndian Dermatology Online Journal
Vineet Relhan   +3 more
openaire   +3 more sources

Circadian regulation of reproduction and neoblast cell division in the catenulid flatworm Stenostomum virginianum (Platyhelminthes)

open access: yesPhotochemistry and Photobiology, EarlyView.
The circadian clock and melatonin coordinate homeostasis in many animals, yet their influence on reproduction and neoblast proliferation has only been shown in triclads. This study demonstrates that the early‐branching catenulid Stenostomum virginianum contains photoreceptive refractile bodies, synthesizes endogenous melatonin, and that exogenous ...
Daniel L. Stanton   +5 more
wiley   +1 more source

Harnessing spatiotemporal melatonin delivery from engineered platforms for targeted microenvironment remodeling in peripheral neuropathy. [PDF]

open access: yesMater Today Bio
Sun M   +11 more
europepmc   +1 more source

The effects of spectrum, irradiance, and duration of exposure on light‐induced melatonin suppression in healthy adults

open access: yesPhotochemistry and Photobiology, EarlyView.
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena   +4 more
wiley   +1 more source

Nocturnal Melatonin Amplitude Collapse Is Associated with Age-Independent Convergence of Microbiome and Glymphatic Biomarkers. [PDF]

open access: yesCurr Issues Mol Biol
Tavartkiladze A   +7 more
europepmc   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

open access: yesPhotochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi   +2 more
wiley   +1 more source

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