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Melatonin and Melatonin Analogues

Sleep Medicine Clinics, 2009
Over the past 25 years, there has been substantial growth in the field of melatonin and melatonin analogues. Following the first demonstration that exogenous melatonin can entrain the mammalian circadian system and the discovery of the phase-shifting and sleep-promoting properties of the hormone in humans, several groups have demonstrated the potential
Shantha M.W. Rajaratnam   +2 more
openaire   +1 more source

Phototoxicity of melatonin

Archives of Pharmacal Research, 1999
Melatonin (MLT), N-acetyl-5-methoxytryptamine, is mainly secreted by the pineal gland. The ultraviolet (UV), infrared (IR) and 1H-NMR spectra of irradiated and non-irradiated MLT were measured, and phototoxicity tests of MLT, anthracene (positive control) and sodium lauryl sulfate (SLS, negative control) were performed.
Y O, Kim   +6 more
openaire   +2 more sources

MELATONIN RADIOIMMUNOASSAY

The Journal of Clinical Endocrinology & Metabolism, 1975
A radioimmunoassay for melatonin has been developed after the raising of anti-melatonin antibodies in rabbits.
J, Arendt, L, Paunier, P C, Sizonenko
openaire   +2 more sources

Melatonin and Aging

2002
Had there been a meeting on melatonin three decades after its discovery, and an assessment of its potential in 1988, perhaps many of the same topics would have been covered as are being addressed after four decades today. However, one feature about melatonin has clearly changed over the past 10 years.
Turek, F.W.   +2 more
openaire   +4 more sources

Melatonin and psychiatry

Biological Psychiatry, 1988
The pineal methoxyindole melatonin remains the most widely studied of the "pineal principles," and in subhuman species, the neuroendocrine status of this hormone is now generally acknowledged. In humans, however, no definitive functional activity for melatonin has yet been convincingly demonstrated, despite the description in recent years of marked ...
A, Miles, D R, Philbrick
openaire   +2 more sources

Melatonin in Plants

2003
A widespread occurrence of melatonin in plant kingdom has been reported. The circadian rhythm in the level of melatonin observed in both unicellular algae and higher plants, suggests a role in regulation of photoperiodic and rhythmic phenomena, i.e. a similar function for melatonin in both plants and animals.
CANIATO, ROSAMARIA   +5 more
openaire   +4 more sources

Alcohol and melatonin

Chronobiology International, 2021
Investigation of the pathogenesis of alcoholism in humans using different methodological approaches has facilitated detection of important biological factors of consequent metabolic diseases, endocrine disorders, and other medical conditions, such as alcoholic cardiomyopathy, alcoholic hypertension, heart and vascular lesions, alcoholic liver disease ...
openaire   +2 more sources

Melatonin

2007
Melatonin is a neurohormone that is secreted by the pineal gland and known to impact the sleep-wake cycle. Melatonin is regarded to be a safe and natural sleep aid. Since many people with tinnitus suffer sleep disturbance, melatonin has been studied as a therapeutic agent for tinnitus. A review of the literature suggests that melatonin has a beneficial
openaire   +2 more sources

Melatonin and Aging

2023
The health problems associated with the aging process are becoming increasingly widespread due to the increase in mean life expectancy taking place globally. While decline of many organ functions is an unavoidable concomitant of senescence, these can be delayed or moderated by a range of factors.
openaire   +2 more sources

Melatonin and the Thyroid

Hormone and Metabolic Research, 1980
Chronic melatonin administration (100 microgram daily for 21 days) to male weanling rats increased basal TSH without altering peripheral hormone levels. There was an increase in radioactive thyroidal iodine uptake in the melatonin treated animals. Melatonin increased the thyroid gland size relative to body weight and increased the total T4 content and ...
J, Gordon, J E, Morley, J M, Hershman
openaire   +2 more sources

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