Results 141 to 150 of about 2,729,675 (338)

Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice

Heliyon
Age-related cardiovascular diseases continue to be important issues that contribute to the societal burden. Unveiling the molecular mechanisms underlying age-related cardiovascular diseases provides novel opportunities to delay aging and facilitate early
Zhenyu Feng, Yang Liu, Yijin Yang, Jie Bai, Qiu-yue Lin, Yun-long Xia, Yunpeng Xie   +6 more
doaj   +1 more source

Role of the Histaminergic System in the Inhibitory Effect of Melatonin on Broiler Chicken Feed Intake [PDF]

Poultry Science Journal
Prior investigations have postulated that melatonin, a prominent hormone produced by the pineal gland, can reduce animal food consumption. This study was designed to evaluate the involvement of central histamine H1 and H2 receptors in regulating ...
Majid Taati, Hassan Norouzian, Vahid Farhadi   +2 more
doaj   +1 more source

Modulation of Melatonin Receptors Regulates Reproductive Physiology: The Impact of Agomelatine on the Estrus Cycle, Gestation, Offspring, and Uterine Contractions in Rats. [PDF]

Physiol Res, 2023
Kacar E, Tan F, Sahinturk S, Zorlu G, Serhatlioglu I, Bulmus O, Ercan Z, Kelestimur H.   +7 more
europepmc   +1 more source

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

The impact of regional, seasonal, and environmental factors on the sleep status of urban residents in China

Sleep Research, EarlyView.
Abstract Background Sleep quality is influenced by various environmental factors, yet their impact across different regions and seasons in China remains understudied. Objective This study evaluated how environmental factors affect sleep quality, duration, and disorders among Chinese urban residents in different regions and seasons.
Youyang Qu, Shuhan Meng, Wanqiao Qi, Guihai Chen, Zan Wang, Jinzhu Yan, Ping Gu, Yanmei Zhu, Zifen Wan, Li Wang, Yuanqing Wang, Zhongming He, Dali Li, Lisan Zhang, Yunhui Lv, Guohui Li, Weimin Qu, Lili Long, Weiping Liu, Ning Li, Jianbin Liu, Wei Wu, Xiaojiang Jiang, Liang Xie, Liying Deng, Xiang Gao, Zhili Huang, Yulan Zhu   +27 more
wiley   +1 more source

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

Sleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang, Shuangyan Li, Dhirendra Paudel, Miaoqin Tan, Bin Zhang   +4 more
wiley   +1 more source

Molecular basis of ligand selectivity for melatonin receptors. [PDF]

RSC Adv, 2023
Cui W, Dong J, Wang S, Vogel H, Zou R, Yuan S.   +5 more
europepmc   +1 more source

Research on sleep quality and influencing factors among medical staff in a tertiary hospital in Anhui Province, China

Sleep Research, EarlyView.
To assess sleep quality and identify key influencing factors among medical staff in a tertiary hospital to support health policy development. Conducted in July 2024 using validated scales: Pittsburgh Sleep Quality Index (PSQI); Depression, Anxiety, and Stress Scale‐21; and Assessed: sleep quality, latency, disturbances, and daytime dysfunction.
Xiao‐Ying Jin, Ting Jiang, Ri‐Hong Wei, Meng‐Dan Chu, Han Li, Shan Zhang, Zeng‐Feng Su   +6 more
wiley   +1 more source

Structural Basis for Agonistic Activity and Selectivity toward Melatonin Receptors hMT1 and hMT2. [PDF]

Int J Mol Sci, 2023
Cantarini M, Rusciano D, Amato R, Canovai A, Cammalleri M, Monte MD, Minnelli C, Laudadio E, Mobbili G, Giorgini G, Galeazzi R.   +10 more
europepmc   +1 more source

Differential involvement of hippocampal angiotensin 1 receptors in learning and memory processes in bulbectomized rats [PDF]

, 2016
There is conflicting evidence regarding the effect of AT1 receptor antagonists on learning and memory processes. The effects of angiotensin II and losartan administration into CA1 hippocampal area on the avoidance performance in olfactory bulbectomized ...
Belcheva, Iren, Belcheva, Stiliana, Ivanova, Margarita, Tashev, Roman   +3 more
core   +1 more source