Results 211 to 220 of about 25,767 (309)

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

Periodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity

, 2004
Valeria Lucini, Marilou Pannacci, Francesco Scaglione, F. Fraschini, Silvia Rivara, Marco Mor, Fabrizio Bordi, Pier Vincenzo Plazzi, Gilberto Spadoni, Annalida Bedini, Giovanni Piersanti, Giuseppe Diamantini, Giorgio Tarzia   +12 more
openalex   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

Mapping the Melatonin Receptor. 6. Melatonin Agonists and Antagonists Derived from 6H-Isoindolo[2,1-a]indoles, 5,6-Dihydroindolo[2,1-a]isoquinolines, and 6,7-Dihydro-5H-benzo[c]azepino[2,1-a]indoles

, 2000
Rüdiger Faust, Peter J. Garratt, Robert J. Jones, Li-Kuan Yeh, Andrew Tsotinis, Maria Panoussopoulou, Theodora Calogeropoulou, Muy‐Teck Teh, David Sugden   +8 more
openalex   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

Experimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz, Yavuz Erden, Çiğdem Tekin, Suat Tekin   +3 more
wiley   +1 more source

Family History and Solar Insolation in Bipolar I Disorder

Acta Psychiatrica Scandinavica, Volume 153, Issue 4, Page 270-278, April 2026.
ABSTRACT Background Sunlight has profound impacts on physical and mental health, beyond vision, including effects on circadian rhythms, alertness, mood, and sleep. A family history of any mood disorders is strongly associated with psychiatric disorders including bipolar disorder.
M. Bauer, T. Glenn, E. D. Achtyes, M. Alda, E. Agaoglu, K. Altınbaş, O. A. Andreassen, E. Angelopoulos, R. Ardau, M. Aydin, Y. Ayhan, C. Baethge, R. Bauer, B. T. Baune, C. Balaban, C. Becerra‐Palars, A. P. Behere, H. Belete, T. Belete, G. Okawa Belizario, F. Bellivier, R. H. Belmaker, F. Benedetti, M. Berk, Y. Bersudsky, Ş. Bicakci, H. Birabwa‐Oketcho, T. D. Bjella, C. Brady, J. Cabrera, M. Cappucciati, A. M. Paredes Castro, W. Chen, E. Y. W. Cheung, S. Chiesa, M. Chanopoulou, M. Crowe, A. Cuomo, S. Dallaspezia, P. Desai, S. Dodd, B. Etain, A. Fagiolini, F. T. Fellendorf, E. Ferensztajn‐Rochowiak, J. G. Fiedorowicz, K. N. Fountoulakis, M. A. Frye, P. A. Geoffroy, M. J. Gitlin, A. Gonzalez‐Pinto, J. F. Gottlieb, P. Grof, B. C. M. Haarman, H. Harima, M. Hasse‐Sousa, C. Henry, L. Hoffding, J. Houenou, M. Imbesi, E. T. Isometsä, M. Ivkovic, S. Janno, S. Johnsen, F. Kapczinski, G. N. Karakatsoulis, M. Kardell, L. V. Kessing, S. J. Kim, B. König, T. L. Kot, M. Koval, M. Kunz, B. Lafer, M. Landén, E. R. Larsen, R. W. Licht, V. M. Ludwig, C. Lopez‐Jaramillo, A. MacKenzie, H. Østergaard Madsen, S. Alberte Kongstad A. Madsen, J. Mahadevan, A. Mahardika, K. Mahfoudh, M. Manchia, W. Marsh, M. Martinez‐Cengotitabengoa, J. Martini, K. Martiny, Y. Mashima, D. M. McLoughlin, A. N. R. Meesters, Y. Meesters, I. Melle, F. Meza‐Urzúa, E. Michaelis, P. Mikolas, Y. Ming Mok, S. Monteith, M. Moorthy, G. Morken, E. Mosca, A. A. Mozzhegorov, R. Munoz, S. V. Mythri, R. K. Nadella, T. Nakanotani, R. Ernst Nielsen, C. O'Donovan, A. Omrani, Y. Osher, U. Ouali, M. Pantovic‐Stefanovic, P. Pariwatcharakul, J. Petite, A. Pfennig, M. Pilhatsch, Y. Pica Ruiz, M. Pinna, M. Pompili, R. Porter, D. Quiroz, F. Diego Rabelo‐da‐Ponte, R. Ramesar, N. Rasgon, W. Ratta‐apha, M. Redahan, M. S. Reddy, A. Reif, E. Z. Reininghaus, J. Gringer Richards, P. Ritter, J. K. Rybakowski, L. Sathyaputri, A. M. Scippa, C. Simhandl, D. Smith, J. Smith, P. W. Stackhouse Jr, D. J. Stein, K. Stilwell, S. Strejilevich, K.‐P. Su, M. Subramaniam, A. Hatim Sulaiman, K. Suominen, A. J. Tanra, Y. Tatebayashi, W. Lin Teh, L. Tondo, C. Torrent, D. Tuinstra, T. Uchida, A. E. Vaaler, E. Vieta, B. Viswanath, C. Volf, K.‐J. Yang, M. Yoldi‐Negrete, O. Kaan Yalcinkaya, A. H. Young, Y. Zgueb, P. C. Whybrow   +163 more
wiley   +1 more source

Reply to Ahluwalia et al.: Contributions of melatonin receptors are tissue-dependent. [PDF]

Proc Natl Acad Sci U S A, 2018
Suofu Y, Carlisle DL, Vilardaga JP, Friedlander RM.   +3 more
europepmc   +1 more source

Artificial intelligence streamlines scientific discovery of drug–target interactions

British Journal of Pharmacology, Volume 183, Issue 8, Page 1673-1690, April 2026.
Abstract Drug discovery is a complicated process through which new therapeutics are identified to prevent and treat specific diseases. Identification of drug–target interactions (DTIs) stands as a pivotal aspect within the realm of drug discovery and development. The traditional process of drug discovery, especially identification of DTIs, is marked by
Yuxin Yang, Feixiong Cheng
wiley   +1 more source

Is there a better way to wean chronic benzodiazepine receptor agonists use by substituting a DORA (and starting CBT-I)?Commentary on Tachibana M, Kanahara N, Oda Y, Hasegawa T, Kimura A, Iyo M. A retrospective clinical practice study comparing the usefulness of dual-orexin receptor antagonists and a melatonin receptor agonist in patients switching from long-term benzodiazepine receptor agonists. J Clin Sleep Med . 2024;20(4):603–613. doi:10.5664/jcsm.10946 [PDF]

Madeleine Grigg‐Damberger
openalex   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, Volume 59, Issue 4, Page 590-613, April 2026.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source