Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Smith‐Magenis Syndrome (SMS) is an uncommon genetic disorder caused by microdeletions of chromosome 17p11.2 including the RAI1 gene, or loss‐of‐function mutations that directly affect RAI1. Due to the involvement of RAI1 in neurodevelopment, SMS leads to typical pathologic features in the behavioral and physical phenotype that must be ...
Edgar Andrés Chavarría‐Martínez +4 more
wiley +1 more source
Glymphatic System Dysfunction in Central Nervous System Diseases
CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.Glymphatic Dysfunction in Neurological Disorders: The glymphatic system is a brain‐wide clearance system that removes neurotoxic waste via AQP4‐mediated CSF‐ISF exchange. Dysfunction through AQP4 mislocalization, BBB injury, and inflammation annihilates clearance and causes acute (stroke, TBI) and chronic disease.
Anwar Zahran +14 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Chamomile contains different bioactive agents such as flavonoids and phytosterols with potential anti‐inflammatory, antioxidant, analgesic, antispasmodic, and antitumor characteristics. According to our findings, animal studies have demonstrated the potential benefits of Chamomile consumption in the treatment of PCOS. In contrast, human studies yielded
Zahra Firoozi +3 more
wiley +1 more source
Melatonin Mitigates Central Sensitization and Nociplastic Pain in Spinal Cord and Dorsal Root Ganglia of FM Rat Model: Modulation of SIRT1/PGC-1α/MAPK/NF-κB Signaling. [PDF]
J Neuroimmune PharmacolOsama J +4 more
europepmc +1 more source
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background and Aims Preterm neonates are at higher risk of cumulative procedural pain at a crucial point in brain development. Several procedures performed in neonatal intensive care units (NICUs) have ineffective or absent pain management protocols. Nonpharmacological interventions are simple to implement and cost‐efficient.
Kristine Kleven, Chirag C. Sheth
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Physiological relevance of autocrine melatonin signaling in pineal and extrapineal sites: a systematic review. [PDF]
Function (Oxf)Ndinganire G +2 more
europepmc +1 more source
Quercetin and Its Nano‐Based Formulations Against Skin Cancer: A Narrative Review
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, chemotherapy, and radiotherapy—often suffer from limitations such as adverse side effects, tumor resistance, and inadequate efficacy.
Mahtab Khanyabzadeh +14 more
wiley +1 more source
Melatonin mitigates hormonal toxicity in cannabis-treated female Wistar rats: involvement of cannabinoid receptor. [PDF]
J Cannabis ResOluwasola A.
europepmc +1 more source
An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract
Journal of Applied Toxicology, Volume 46, Issue 3, Page 932-949, March 2026.ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston +2 more
wiley +1 more source
Melatonin Biosynthesis, Receptors, and the Microbiota-Tryptophan-Melatonin Axis: A Shared Dysbiosis Signature Across Cardiac Arrhythmias, Epilepsy, Malignant Proliferation, and Cognitive Trajectories. [PDF]
Int J Mol SciTavartkiladze A +13 more
europepmc +1 more source