Results 91 to 100 of about 13,623 (189)
Scientifica, Volume 2025, Issue 1, 2025.Malaria remains a major global health challenge, necessitating the discovery of novel therapeutic agents. This study investigates secondary metabolites from Penicillium spp. as potential inhibitors of Plasmodium falciparum lactate dehydrogenase (PfLDH), a critical enzyme in the parasite’s glycolytic pathway.
Imran Sama-ae +12 more
wiley +1 more source
Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial Cells [PDF]
, 2015 Members of the Burkholderia species can cause a range of severe, often fatal, respiratory diseases. A variety of in vitro models of infection have been developed in an attempt to elucidate the mechanism by which Burkholderia spp.
Graeme C. Clark +2 more
core +1 more source
CRISPR/Cas system and its application in the diagnosis of animal infectious diseases
The FASEB Journal, Volume 38, Issue 24, 31 December 2024.CRISPR‐based diagnostic platforms have transformed the molecular diagnostic field due to their outstanding ultra‐sensitive nucleic acid detecting capabilities. In this review, we highlighted the application of currently available CRISPR integrated setups on the diagnosis of animal infectious diseases.
Hafiz Muhammad Hamza Rasool +3 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 13, Issue 9, September 2024.Abstract Membrane vesicles (MVs) are produced by species across all domains of life and have diverse physiological functions as well as promising applications. While the mechanisms for vesiculation in Gram‐negative bacteria are well‐established, the genetic determinants and regulatory factors responsible for MV biogenesis in Gram‐positive bacteria ...
Jia Li +12 more
wiley +1 more source
Clinical and Imaging Findings of Musculoskeletal Melioidosis in the Right Hip: A Case Report
대한영상의학회지, 2018 Melioidosis is an infectious disease caused by a Gram-negative bacterium thought to be caused Burkholderia pseudomallei. This disease is endemic in tropical regions, but is not endemic and is rarely encountered in Korea.
Myung Hyun Kim, Tong Jin Chun
doaj +1 more source
Melioidosis, Singapore, 2003–2014
Emerging Infectious Diseases, 2018 In contrast with northern Australia and Thailand, in Singapore the incidence of melioidosis and co-incidence of melioidosis and pneumonia have declined. Burkholderia pseudomallei deep abscesses increased 20.4% during 2003–2014.
Long Pang +8 more
doaj +1 more source
Australasian Journal of Dermatology, Volume 65, Issue 5, Page 462-466, August 2024.Abstract Background/Objectives Royal Darwin Hospital (RDH) is the sole public dermatology service in the Northern Territory (NT). Prescription of biologic therapies (BT) in the NT is uniquely challenging, with remote populations carrying a high tropical disease burden.
Lucinda Adams +2 more
wiley +1 more source
The characteristics and clinical course of patients with melioidosis and cancer.
PLoS Neglected Tropical DiseasesBackgroundPatients with an active cancer are more likely to develop melioidosis, but the characteristics and clinical course of melioidosis in patients with cancer have not been examined in detail.
Tej Shukla +4 more
doaj +1 more source
Fatal melioidosis in a captive elephant trunk snake (Acrochordus javanicus) in Kuala Lumpur, Malaysia [PDF]
, 2016 An adult female Elephant Trunk Snake (Acrochordus javanicus) was reported to have been weak and inappetent for five days. The following morning the snake found dead, while in the process of shedding its skin.
Abba, Yusuf +4 more
core
Burkholderia pseudomallei Sequence Type 46 Transmission from Asia to Australia
Emerging Infectious DiseasesMelioidosis is caused by the environmental pathogen Burkholderia pseudomallei. Among 1,331 patients with melioidosis during 1989–2023 in the Darwin Prospective Melioidosis Study in Australia, we identified 6 locally acquired cases caused by B ...
Ella M. Meumann +6 more
doaj +1 more source