Results 51 to 60 of about 36,266 (311)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Geodynamic Models of Melt Generation and Extraction at Mid-Ocean Ridges [PDF]

open access: yesOceanography, 2012
It is widely accepted that plate divergence at mid-ocean ridges drives mantle flow, mantle melting, and the formation of new oceanic crust. However, many of the details of this process remain obscure because of the inaccessibility of the mantle to direct
Patricia M. Gregg   +3 more
doaj  

Highly efficient Fe separation induced by Fe-containing particle agglomeration in Al-7Si-0.3Mg alloy melt

open access: yesJournal of Materials Research and Technology, 2022
In this paper, the melt turbulence process was introduced to result in Fe-containing particle agglomeration and achieve highly efficient Fe separation in Al-Si alloy melt. Microstructure analysis, 3D-morphology extraction, X-ray microscopy (μCT) analysis
Xiaozu Zhang   +6 more
doaj   +1 more source

MeltMigrator : a MATLAB-based software for modeling three-dimensional melt migration and crustal thickness variations at mid-ocean ridges following a rules-based approach [PDF]

open access: yes, 2017
Author Posting. © American Geophysical Union, 2017. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry, Geophysics, Geosystems 18 (2017):
Bai, Hailong   +2 more
core   +1 more source

A model of episodic melt extraction for plumes [PDF]

open access: yesJournal of Geophysical Research: Solid Earth, 2006
A model of melt segregation and extraction within rising plumes is proposed. It is based on two‐phase porous flow within the partially molten region, combined with only three extraction parameters. The conservation equations of mass, momentum, and energy are solved for a two‐phase melt matrix system.
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Glacial cycles drive variations in the production of oceanic crust

open access: yes, 2014
Glacial cycles redistribute water between oceans and continents causing pressure changes in the upper mantle, with consequences for melting of Earth's interior.
Crowley, John W.   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effect of annealing of ZnSe:Cr crystals in Bi(Zn) melt on the intensity of radiation bands of Cr ions

open access: yesMoldavian Journal of the Physical Sciences, 2010
The photoluminescence in visible and near-IR spectral range of ZnSe:Cr as-grown and annealed in Bi(Zn) melt crystals was investigated at room temperature.
Culiuc, Leonid   +3 more
doaj  

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