Results 101 to 110 of about 128,460 (306)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

A model of episodic melt extraction for plumes [PDF]

Journal of Geophysical Research: Solid Earth, 2006
A model of melt segregation and extraction within rising plumes is proposed. It is based on two‐phase porous flow within the partially molten region, combined with only three extraction parameters. The conservation equations of mass, momentum, and energy are solved for a two‐phase melt matrix system.
openaire   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic [PDF]

, 2018
Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic (March 25 - 27, 2018 -- The University of New Hampshire) paired two of NSF\u27s 10 Big Ideas: Navigating the New Arctic and Growing Convergence ...
Ashcraft, Catherine M, Brewer, Jennifer F, Burakowski, Elizabeth, Coffin, Jaed M, Dibb, Jack E, Duderstadt, Katharine A, Hamilton, Lawrence C, Kinner, Nancy E, Mayer, Larry A., Miksis-Olds, Jennifer L, Salisbury, Joseph, Seger, Kerri D, Varner, Ruth K., Wake, Cameron P.   +13 more
core   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

A lightweight machine learning-based melt pond extraction scheme for oblique shipborne imagery

International Journal of Digital Earth
High-resolution shipborne optical images can accurately capture the melt ponds on Arctic sea ice surfaces, serving as an important supplement to satellite remote sensing.
Jiaru Zhou, Peng Lu, Xuewei Li, Miao Yu, Hang Zhang, Puzhen Huo, Qingkai Wang, Huawei Shao, Zongxing Li, Zhijun Li   +9 more
doaj   +1 more source

Determination of Calibration Characteristics of X-Ray Fluorescent Analysis of Rhenium

Eurasian Chemico-Technological Journal, 2011
Extraction concentration of rhenium by a melt of tetraoctylammonium bromide in paraffin was used with the aim of preparation of calibration samples for roentgen fluorescent analysis. The calibration characteristics of the roentgen fluorescent analysis of
A. V. Troeglazova, E. V. Zlobina, A. Yu. Sokolov, A. K. Zhangalieva   +3 more
doaj   +1 more source