Results 101 to 110 of about 1,420,609 (296)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

A qualitative and quantitative investigation of nonmetallic inclusions in molten Al–Mg, Al–Cu, and Al–Zn–Mg–Cu alloys

Journal of Materials Research and Technology
In this work, a qualitative and quantitative investigation on inclusions in molten Al–Mg, Al–Cu, and Al–Zn–Mg–Cu alloys, and the evolution behavior of inclusions in these three alloys during off-line and on-line purification steps were studied via the ...
Yuanchun Huang, Xianbin Gao, Yu Liu, Zhiyong Sheng, Xi Fan   +4 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Melt inclusion vapour bubbles: the hidden reservoir for major and volatile elements. [PDF]

Sci Rep, 2020
Venugopal S, Schiavi F, Moune S, Bolfan-Casanova N, Druitt T, Williams-Jones G.   +5 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Effects of laser-beam diameter on melt pool characteristics and grain formation in Fe-3.4 wt%Si alloy made by powder bed fusion

Journal of Materials Research and Technology
This study explores the interaction between laser-induced thermal processes and fluid dynamics that govern the formation and morphology of the melt pool during Laser Powder Bed Fusion of Fe-3.4 wt%Si powder.
Ho Sung Jang, Su Heon Kim, Geon-Woo Park, Jong Bae Jeon, Donghwi Kim, Yoon Suk Choi, Sunmi Shin   +6 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

VolFe: an open-source Python package for calculating melt-vapour equilibria including silicate melt, carbon, hydrogen, sulfur, and noble gases

Volcanica
VolFe is an open-source flexible and adaptable thermodynamic framework in Python for calculating the equilibrium composition of melt and vapour. VolFe considers basaltic through rhyolitic melts including the volatiles carbon, hydrogen, sulfur, and the ...
Ery Hughes, Philippa Liggins, Penny Wieser, Edward Stolper   +3 more
doaj   +1 more source

Mechanical, Rheological, and Bioactivity Properties of Ultra High-Molecular-Weight Polyethylene Bioactive Composites Containing Polyethylene Glycol and Hydroxyapatite

The Scientific World Journal, 2012
Ultrahigh-molecular-weight polyethylene/high-density polyethylene (UHMWPE/HDPE) blends prepared using polyethylene glycol PEG as the processing aid and hydroxyapatite (HA) as the reinforcing filler were found to be highly processable using conventional ...
Mazatusziha Ahmad, Mat Uzir Wahit, Mohammed Rafiq Abdul Kadir, Khairul Zaman Mohd Dahlan   +3 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source