Results 101 to 110 of about 1,138,785 (296)

Surface melting of methane and methane film on magnesium oxide

, 2000
Experiments on surface melting of several organic materials have shown contradictory results. We study the Van der Waals interactions between interfaces in surface melting of the bulk CH_4 and interfacial melting of the CH_4 film on the MgO substrate ...
Ancilotto, Beaglehole, Bienfait, Bienfait, Bilalbegović, Chandavarkar, Chen, Chen, Chernov, Dal Corso, Dash, de Jeu, Djurišić, Dzyaloshinskii, Elbaum, Freitag, G. Bilalbegović, Hough, Martonchik, N. Klipa, Parsegian, Plomp, Pluis, Sabisky, van Pinxteren, Wilen, Wong   +26 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Shock-induced melting of MgSiO_3 perovskite and implications for melts in Earth's lowermost mantle [PDF]

, 2004
New shock wave equation of state (EOS) data for enstatite and MgSiO_3 glass constrain the density change upon melting of Mg-silicate perovskite up to 200 GPa. The melt becomes denser than perovskite near the base of Earth's lower mantle.
Ahrens, Thomas J., Akins, Joseph A., Asimow, Paul D., Luo, Sheng-Nian   +3 more
core  

Flux-line entanglement as the mechanism of melting transition in high-temperature superconductors in a magnetic field

, 1999
The mechanism of the flux-line-lattice (FLL) melting in anisotropic high-T_c superconductors in ${\bf B}\parallel {\bf \hat{c}}$ is clarified by Monte Carlo simulations of the 3D frustrated XY model.
A. Houghton, A. Schilling, A. Schilling, A.E. Koshelev, A.K. Nguyen, A.K. Nguyen, A.K. Nguyen, D.R. Nelson, D.R. Nelson, D.S. Fisher, E. Zeldov, G. Blatter, G. Blatter, H. Nordborg, H. Nordborg, H. Safar, J. Hu, J.A. Fendrich, M.E. Fisher, Masashi Tachiki, R. Šás̆ik, R.E. Hetzel, S. Ryu, S. Ryu, U. Welp, W.K. Kwok, X. Hu, X. Hu, X. Hu, Xiao Hu, Y.-H. Li, Y.-H. Li, Yoshihiko Nonomura, Z. Tesanovic, Z. Tesanovic   +34 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Geochemical variation at the Hawaiian hot spot caused by upper mantle dynamics and melting of a heterogeneous plume

Geochemistry, Geophysics, Geosystems, 2008
Geochemical variations within the young Hawaiian Islands occur in two particularly prominent forms: differences between volcanic stages and differences between the “Loa” and “Kea” subchains.
Todd Anthony Bianco, Garrett Ito, Jeroen van Hunen, Maxim D. Ballmer, John J. Mahoney   +4 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source