Results 31 to 40 of about 329,505 (267)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Close contact melting of ice on circular cylinders
Nihon Kikai Gakkai ronbunshu, 2018 Close contact melting of solid phase on hot circular cylinders horizontally arranged in line was studied analytically. The analytical results were compared with experiment.
Yasuaki SHIINA +2 more
doaj +1 more source
Frontiers in Chemistry, 2022 This study aims to evaluate the melting characteristics of a phase change material (PCM) in a latent heat storage system equipped with hemispherical and quarter-spherical fins.
Azher M. Abed +9 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
EXPERIMENTAL RESEARCH OF DENDRITIC CRYSTALS FORMATION ON METAL SURFACE BY LASER RADIATION [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2019 Subject of research. We study conditions of fractal crystals growth on the high-temperature material surface under pulsed laser radiation impact. Method.
, , , N. A. Aganin, , +5 more
doaj
Geochemistry, Geophysics, Geosystems, 2012 Continental rifting is accompanied by lithospheric thinning and decompressional melting. After extraction, melt is intruded at shallower depth thereby heating and weakening the lithosphere.
Harro Schmeling, Herbert Wallner
doaj +1 more source
Energies, 2023 Analytical, computational and experimental investigations directed at improving the performance of latent heat thermal energy storage systems that utilize high thermal conductivity fins in direct contact with phase change materials are reviewed ...
Wenwen Ye +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source