Results 41 to 50 of about 329,505 (267)

Study on Reductive Smelting of High-Iron Red Mud for Iron Recovery

Metals, 2022
In this paper, the characteristics and current problems associated with red mud and the progress of research on iron extraction from high-iron red mud are briefly described.
Xuewei Yang, Xin Chen, Tingan Zhang, Jiayuan Ye, Guozhi Lv, Jinshan Zhang   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Melting in Shell-and-Tube and Shell-and-Coil Thermal Energy Storage: Analytical Correlation for Melting Fraction

Energies
The following study investigated the melting behavior of coconut oil as a phase-change material in shell-and-tube and shell-and-coil thermal energy storage systems.
Michał Rogowski, Maciej Fabrykiewicz, Rafał Andrzejczyk   +2 more
doaj   +1 more source

Numerical Study of Effect of Thermocapillary Convection on Melting Process of Phase Change Material subjected to Local Heating

Journal of Thermal Science and Technology, 2013
We numerically investigate the effect of thermocapillary convection on melting and deforming processes of Phase Change Material (PCM) subjected to local heating. Mass, momentum and energy conservation equations are solved in a 2-D system based on a fixed
Yangkyun KIM, Akter HOSSAIN, Yuji NAKAMURA   +2 more
doaj   +1 more source

Structure Optimization of Longitudinal Rectangular Fins to Improve the Melting Performance of Phase Change Materials through Genetic Algorithm

Energies, 2022
In this paper, the structural parameters of longitudinal rectangular fins used in a horizontal shell-and-tube latent heat storage unit (LHSU) are optimized to increase the melting rate of phase-change materials. The influence of natural convection on the
Yang Xu, Hang Yin, Chen He, Yong Wei, Ming Cui, Zhang-Jing Zheng   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Critical Melting–Freezing Pretreatment Enhances Enzymatic Hydrolysis for Porous Starch Preparation: Role of Partial Structural Weakening and Surface Modification

Foods
In this study, critical melting followed by freeze–thaw (CMFT) pretreatment was employed as an effective strategy to partially weaken and modify the surface structure of starch, enhancing enzymatic hydrolysis (EH) for porous starch preparation.
Chen Zhang, Chu-Yun Wu, Shi-Qi Qian, Yu-Yan Zhang, Ya-Li Liu, Xin-Yu Li, Shi-Yi Wang, Jian-Ya Qian   +7 more
doaj   +1 more source

Enhancement of the Melting of an Ice Cylinder by the Combination with the Condensation of a Saturated Steam Flow

Journal of Thermal Science and Technology, 2011
Melting of an ice by a steam is sometimes employed, for example, to remove a frost, an ice, and a snow that adhered to the structure surface. It is usually regarded that the melting performance by steam is naturally higher than that by high-temperature ...
Masahiko YAMADA, Makoto OKADA
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source