Results 61 to 70 of about 327,878 (269)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Investigation of fatty acid composition, thermal and rheological behavior of yak, cow and horse fats

MANAS: Journal of Engineering, 2019
The objective of this paper was tostudy the fatty acid composition, and thermal and rheological behavior of Kyrgyz yak (Bos grunniens)visceral fats compared to visceral fats of cow (Bos taurus) and horse (Equuscaballus).
Peter Fischer, Jamila Smanalieva, Zhyldyzai Ozbekova, Asylbek Kulmyrzaev   +3 more
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Observation of Surface Melting

Physical Review Letters, 1985
Ion shadowing and blocking measurements show that the solid-liquid transition at the (110) surface of lead starts at approximately 40 K below the bulk melting point of lead ${T}_{m}$. The thickness of the liquid surface film increases dramatically as the temperature approaches ${T}_{m}$.
Frenken, J.W.M., Veen, J.F. van der
openaire   +4 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

SYSTEM EXHAUST HEAT FROM ELEMENTS OF CEA ON THE BASIS OF PRAVASIS THERMAL BATTERIES

Вестник Дагестанского государственного технического университета: Технические науки, 2016
Considered design systems exhaust heat from the elements REA mode intermittent heat. Describes their applications and advantages over existing analogs of being more reliable performance and lower limits on the pause in the work of the electronic device.
T. A. Ismailov, D. V. Evdulov, O. V. Evdulov   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

USING EXTERNAL ELECTRIC FIELDS WHEN IMPROVING QUALITY OF ALLOYS IN MELT IN MELTING UNITS

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2017
Some advanced methods for alloy composition regulation at negligible consumption of slag-forming additives are suggested. When implementing the proposed technology, the slag functions as a protector and electric conductor, and redox processes are ...
A. P. Laskovnev, A. I. Harast, E. V. Kryvonosova   +2 more
doaj  

Melting of the Snow Cover in the Polish Tatra Mountains – Long-Term Changes and the Impact of Atmospheric Circulation

Quaestiones Geographicae
The aim of the research is to present the annual distribution and long-term changes in the melting of the snow cover in the Tatras. An additional aim is to explain the causes of rapid snow cover melt related to atmospheric circulation.
Jankowska Zuzanna, Falarz Małgorzata
doaj   +1 more source

Melting process and the equilibrium melting temperature of polychlorotrifluoroethylene

Journal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1962
A new method of estimating the equilibrium melting temperature, T(m), of a polymer is described, and applied to polychlorotrifluoroethylene (PCTFE). Experimentally determined values of the so-called observed melting point, [Formula: see text] , are plotted as a function of the isothermal crystallization temperature, T(x).
Hoffman, John D., Weeks, James J.
openaire   +1 more source