Results 71 to 80 of about 1,624,941 (389)

Reducing porosity in AlSi10Mg parts processed by selective laser melting

open access: yes, 2014
Selective laser melting (SLM) is widely gaining popularity as an alternative manufacturing technique for complex and customized parts. SLM is a near net shape process with minimal post processing machining required dependent upon final application.
N. Aboulkhair   +3 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Surface melting of methane and methane film on magnesium oxide

open access: yes, 2000
Experiments on surface melting of several organic materials have shown contradictory results. We study the Van der Waals interactions between interfaces in surface melting of the bulk CH_4 and interfacial melting of the CH_4 film on the MgO substrate ...
Ancilotto   +26 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Study on the effects of initial ice layer and temperature distribution on the redistribution of D2 fuel layer in a cryogenic target

open access: yesNuclear Fusion
Inertial confinement fusion (ICF) is one of the primary methods for achieving controlled nuclear fusion, which is closely related to energy security and national security.
Yina Yao   +5 more
doaj   +1 more source

Holographic Meson Melting

open access: yes, 2007
The plasma phase at high temperatures of a strongly coupled gauge theory can be holographically modelled by an AdS black hole. Matter in the fundamental representation and in the quenched approximation is introduced through embedding D7-branes in the AdS-
A. Karch   +35 more
core   +4 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A Review of Heat Transfer and Numerical Modeling for Scrap Melting in Steelmaking Converters

open access: yesMetals
Steel is an important product in many engineering sectors; however, steelmaking remains one of the largest CO2 emitters. Therefore, new governmental policies drive the steelmaking industry toward a cleaner and more sustainable operation such as the gas ...
Mohammed B. A. Hassan   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Flux-line entanglement as the mechanism of melting transition in high-temperature superconductors in a magnetic field

open access: yes, 1999
The mechanism of the flux-line-lattice (FLL) melting in anisotropic high-T_c superconductors in ${\bf B}\parallel {\bf \hat{c}}$ is clarified by Monte Carlo simulations of the 3D frustrated XY model.
A. Houghton   +34 more
core   +1 more source

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