Results 141 to 150 of about 671,733 (267)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Estimated unit costs of anaemia interventions for women of reproductive age in 193 UN member states: a costing study. [PDF]

Lancet Haematol
Oliver VL, Wang Y, Leung S, Blythe R, Glover-Wright C, Holloway-Brown J, Bode M, Pasricha SR, Carvalho N.   +8 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Current status of radiologist staffing, education and training in the 27 EU Member States. [PDF]

Insights Imaging
Brady AP, Paulo G, Brkljacic B, Loewe C, Szucsich M, Hierath M, European Society of Radiology.   +6 more
europepmc   +1 more source

Supporting the Manufacturing of Medical Supplies in Africa: Collaboration Between Africa CDC, Partners, and Member States. [PDF]

Glob Health Sci Pract, 2023
Mohammed A, Idris-Dantata H, Okwor T, Tanui P, Paintsil E, Kabwe PC, Alimi Y, Tajudeen R, Mankoula W, Ilesanmi OS, Balogun MS, Ihekweazu C, Hornsey E, Ogbuagu O.   +13 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Integration of family planning and nutrition programmes in 64 WHO member states of Africa, Eastern Mediterranean and South-East Asia regions: findings from a survey of Ministry of Health officials. [PDF]

BMJ Glob Health
Shah IH, Ali M, Habib NA, Baloch AA, Ouedraogo L, Aderoba A, Gholbzouri K, Upadhyay MT, Jarathilake A, Fawzi W, Partap U.   +10 more
europepmc   +1 more source

Inequity of maternal-child health services in ASEAN member states from 1993 to 2021. [PDF]

Int J Equity Health, 2023
Feng Y, Maimaitiming M, Shi J, Wang M, Li N, Jin Y, Zheng ZJ.   +6 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

European citizens' support for humanitarian aid funded by the EU: a secondary analysis of Eurobarometer data from the 27 EU Member States. [PDF]

Lancet Reg Health Eur
Ktenidis G, Vardavas CI, Filippidis FT, Orfanos P, Lagiou P.   +4 more
europepmc   +1 more source