Results 121 to 130 of about 6,904,879 (418)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Nitrogen Production by Efficiently Removing Oxygen From Air Using a Perovskite Hollow-Fiber Membrane With Porous Catalytic Layer

Frontiers in Chemistry, 2018
Nowadays, nitrogen is mainly produced from air by cryogenic separation, pressure-swing adsorption (PSA) and polymeric membrane technology. In this paper, we report a perovskite membrane-based nitrogen production route, which is basically driven by ...
Tianmiao Hu, Tianmiao Hu, Hangyue Zhou, Hangyue Zhou, Hui Peng, Heqing Jiang   +5 more
doaj   +1 more source

membranes

, 2020
At present, a significant progress has been achieved in the field of water filtration. in this regard, membrane technology has played a crucial role. Membrane technology is a rapidly growing research area with several real times applications such as gas and aqueous purification.
openaire   +3 more sources

Membrane systems with proteins embedded in membranes

Theoretical Computer Science, 2008
Membrane computing is a biologically inspired computational paradigm. Motivated by brane calculi we investigate membrane systems which differ from conventional membrane systems by the following features: (1) biomolecules (proteins) can move through the regions of the systems, and can attach onto (and de-attach from) membranes, and (2 ...
Brijder R., Cavaliere M., Riscos-Núñez A., Rozenberg G., Sburlan D.   +4 more
openaire   +3 more sources

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Controllable ion transport by surface-charged graphene oxide membrane

Nature Communications, 2019
Ion transport is crucial for biological systems and membrane-based technology. Atomic-thick two-dimensional materials, especially graphene oxide (GO), have emerged as ideal building blocks for developing synthetic membranes for ion transport.
Mengchen Zhang, Kecheng Guan, Yufan Ji, Gongpin Liu, W. Jin, N. Xu   +5 more
semanticscholar   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Fouling-resistant reverse osmosis membranes grafted with 2-aminoethanethiol having a low interaction energy with charged foulants

npj Clean Water
Many fouling-resistant materials have been grafted or coated on the RO membrane surface for fouling-resistance. However, these modified RO membranes still exhibit a fast flux drop towards small charged organic foulants.
Jun Xiao, Shuang Hao, Yiwen Qin, Pengfei Qi, Zhaoqian Zhang, Yunxia Hu   +5 more
doaj   +1 more source

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

Science, 2018
Fine-tuning pyroptosis with ESCRT-III Pyroptosis is an inflammatory form of cell death induced by select caspases downstream of inflammasome complexes. These caspases cleave gasdermin D (GSDMD), whose N-terminal fragments quickly form large permeability ...
S. Rühl, K. Shkarina, B. Demarco, Rosalie Heilig, J. C. Santos, P. Brož   +5 more
semanticscholar   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source