Results 201 to 210 of about 6,029,360 (328)
Simultaneous voltage-gated control of ion and water transport in Zr<sub>4</sub>-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> nanochannel membranes. [PDF]
Zhang Y +13 more
europepmc +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A Large-Area Uniform Three-Dimensional Covalent Organic Framework Membrane for Stabilizing Li-Metal Electrodes via Solvation Cages. [PDF]
Tang Z +9 more
europepmc +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Adult Case of Congenital Intratympanic Membrane Cholesteatoma. [PDF]
Fukui J +7 more
europepmc +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Proton-conducting polymer electrolyte membranes based on sulfonated PEEK and blends of protic ionic liquids with different acidities. [PDF]
Theußl V +5 more
europepmc +1 more source

