Results 71 to 80 of about 5,501,453 (303)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

Molecular Systems Biology, 2012
The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia, Germaine Goh, Victor Racine, Susanne Ng, Pankaj Kumar, Frederic Bard   +5 more
doaj   +1 more source

Membrane fouling monitoring by 3ω sensing

Scientific Reports, 2023
Membrane fouling significantly reduces membrane permeability, leading to higher operational expenses. In situ monitoring of membrane fouling can potentially be used to reduce operation cost by optimizing operational parameters and cleaning conditions. In
Mads Koustrup Jørgensen, Frederikke Kildeberg Paulsen, Anders Bentien, Astrid Ræbild Kjul, Maiken Poulsen, Louise Mailund Mikkelsen, Nikitha Thavaneswaran, Simon Abildgaard Hansen, Pernille Krogsager Jensen, Jacob Andersen, David N. Østedgaard-Munck, Jan Dimon Bendtsen, Morten Lykkegaard Christensen   +12 more
doaj   +1 more source

Effect of Membrane Exposure on Guided Bone Regeneration: A Systematic Review and Meta‐Analysis [PDF]

, 2018
Aims: This review aimed at investigating the effect of membrane exposure on guided bone regeneration (GBR) outcomes at peri-implant sites and edentulous ridges.
Allen, Annibali, Antoun, Arx, Arx, Arx, Assenza, Bahat, Bartee, Buser, Buser, Buser, Chao, Chiapasco, Chiapasco, Chiapasco, Chin, Cordaro, Cordaro, Cummings, Friedmann, Fu, Gher, Greenstein, Her, Hoffmann, Kfir, Lee, Liberati, Lim, Lindfors, Lizio, Lorenzoni, Lorenzoni, Louis, Lyford, Machtei, Mattout, Mellonig, Meloni, Merli, Misch, Miyamoto, Nowzari, Park, Park, Parodi, Proussaefs, Proussaefs, Proussaefs, Rakhmatia, Seibert, Sethi, Shea, Simion, Simion, Slim, Spray, Tal, Tarnow, Tawil, Torres, Uehara, Urban, Urban, Waasdorp, Wang, Wang, Wang, Wessing, Zitzmann   +70 more
core   +2 more sources

Biological membranes [PDF]

Essays in Biochemistry, 2015
Biological membranes allow life as we know it to exist. They form cells and enable separation between the inside and outside of an organism, controlling by means of their selective permeability which substances enter and leave. By allowing gradients of ions to be created across them, membranes also enable living organisms to generate energy.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Modelling of Ion Transport in Electromembrane Systems: Impacts of Membrane Bulk and Surface Heterogeneity

Applied Sciences, 2018
Artificial charged membranes, similar to the biological membranes, are self-assembled nanostructured materials constructed from macromolecules.
Victor Nikonenko, Andrey Nebavsky, Semyon Mareev, Anna Kovalenko, Mahamet Urtenov, Gerald Pourcelly   +5 more
doaj   +1 more source

The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes

Communications Biology, 2023
In arterial myocytes, the canonical function of voltage-gated CaV1.2 and KV2.1 channels is to induce myocyte contraction and relaxation through their responses to membrane depolarization, respectively.
Collin Matsumoto, Samantha C. O’Dwyer, Declan Manning, Gonzalo Hernandez-Hernandez, Paula Rhana, Zhihui Fong, Daisuke Sato, Colleen E. Clancy, Nicholas C. Vierra, James S. Trimmer, L. Fernando Santana   +10 more
doaj   +1 more source

Membrane tethering [PDF]

F1000Prime Reports, 2014
Membrane trafficking depends on transport vesicles and carriers docking and fusing with the target organelle for the delivery of cargo. Membrane tethers and small guanosine triphosphatases (GTPases) mediate the docking of transport vesicles/carriers to enhance the efficiency of the subsequent SNARE (soluble N-ethylmaleimide-sensitive factor attachment ...
Chia, PZC, Gleeson, PA
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source