Results 71 to 80 of about 4,320,334 (318)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2021 The success of osmotically-driven membrane (OM) technology relies critically on high-performance membranes. Yet trade-off of membrane properties, often further complicated by the strongly non-linear dependence of OM performance on them, imposes important
Wei, Jing +5 more
core +1 more source
RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells
Molecular Systems Biology, 2012 The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2016 Membrane fouling by particulates is largely driven by permeate drag that causes the foulants to move towards the membrane. Cross-flow is used to induce shear at the membrane surface to mitigate the fouling.
Fane, Anthony Gordon +5 more
core +1 more source
Thin film composite hollow fibre membrane for pharmaceutical concentration and solvent recovery
, 2021 A 100-piece hollow fibre thin-film composite membrane module was successfully developed for pharmaceutical concentration and solvent recovery. To increase its packing density, thinner P84 polyimide hollow fibre substrates were spun using a smaller ...
Goh, Keng Siang +4 more
core +1 more source
Membrane fouling monitoring by 3ω sensing
Scientific Reports, 2023 Membrane fouling significantly reduces membrane permeability, leading to higher operational expenses. In situ monitoring of membrane fouling can potentially be used to reduce operation cost by optimizing operational parameters and cleaning conditions. In
Mads Koustrup Jørgensen +12 more
doaj +1 more source
Cell, 2003 Membrane fusion, one of the most fundamental processes in life, occurs when two separate lipid membranes merge into a single continuous bilayer. Fusion reactions share common features, but are catalyzed by diverse proteins. These proteins mediate the initial recognition of the membranes that are destined for fusion and pull the membranes close together
Jahn, R., Lang, T., Suedhof, T.
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Advanced ScienceEfficient lithium extraction from brines remains challenging due to the comparable hydrated radii of Li+ and Mg2+ and the extreme ionic strength of the feed solutions. In this work, a reconstructed polyamide (PA) nanofiltration membrane was developed via
Shuzhen Zhao +9 more
doaj +1 more source