Results 141 to 150 of about 77,483 (239)
Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux +6 more
wiley +1 more source
Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine
Small, EarlyView.Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa +18 more
wiley +1 more source
Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?
Environmental Toxicology, EarlyView.ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves +3 more
wiley +1 more source
Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption
Environmental Toxicology, EarlyView.ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim +10 more
wiley +1 more source
An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda +6 more
wiley +1 more source
Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus
Yeast, EarlyView.Yeasts and related fungi isolated from cacti or nearby non‐cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host. ABSTRACT Together with other fungi, yeasts make up a significant component of the plant microbiome. As the planet warms, cacti expand their range.
Alya N. Hussain +2 more
wiley +1 more source
Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7
Yeast, EarlyView.ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley +1 more source
Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses. [PDF]
Adv Virus Res, 2017 Bigalke JM, Heldwein EE.
europepmc +1 more source
Reconstitution of Membrane Budding with Unilamellar Vesicles [PDF]
, 2009 Anna V. Shnyrova, Joshua Zimmerberg
openaire +1 more source
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant phenology, while genetically determined, is highly responsive to environmental drivers such as soil nutrient availability and disturbance. As an essential micronutrient, zinc (Zn) plays a critical role in plant development by regulating key processes including RNA
Qiuhua Li +10 more
wiley +1 more source