Function of Torsin AAA+ ATPases in Pseudorabies Virus Nuclear Egress [PDF]
Cells, 2020 Newly assembled herpesvirus nucleocapsids traverse the intact nuclear envelope by a vesicle-mediated nucleo-cytoplasmic transport for final virion maturation in the cytoplasm.
Julia E. Hölper +4 more
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Herpesvirus Nuclear Egress across the Outer Nuclear Membrane [PDF]
Viruses, 2021 Herpesvirus capsids are assembled in the nucleus and undergo a two-step process to cross the nuclear envelope. Capsids bud into the inner nuclear membrane (INM) aided by the nuclear egress complex (NEC) proteins UL31/34.
Richard J. Roller, David C. Johnson
doaj +6 more sources
A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex [PDF]
Pharmaceuticals, 2022 The replication of human cytomegalovirus (HCMV) involves a process termed nuclear egress, which enables translocation of newly formed viral capsids from the nucleus into the cytoplasm.
Sewar Alkhashrom +7 more
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Host and Viral Factors Involved in Nuclear Egress of Herpes Simplex Virus 1 [PDF]
Viruses, 2021 Herpes simplex virus 1 (HSV-1) replicates its genome and packages it into capsids within the nucleus. HSV-1 has evolved a complex mechanism of nuclear egress whereby nascent capsids bud on the inner nuclear membrane to form perinuclear virions that ...
Jun Arii
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ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid [PDF]
Journal of VirologyHerpesviruses replicate their genomes and package them into capsids within the host cell nucleus. These capsids must then translocate from the nucleus to the cytoplasm through a process designated nuclear egress. The virus-encoded nuclear egress complex (
Aila Gulijiahani +5 more
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G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids [PDF]
Frontiers in Cell and Developmental Biology, 2022 The nuclear export factor CRM1-mediated pathway is known to be important for the nuclear egress of progeny parvovirus capsids in the host cells with virus-mediated cell cycle arrest at G2/M.
Salla Mattola +11 more
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Role of Vesicle-Associated Membrane Protein-Associated Proteins (VAP) A and VAPB in Nuclear Egress of the Alphaherpesvirus Pseudorabies Virus [PDF]
Viruses, 2021 The molecular mechanism affecting translocation of newly synthesized herpesvirus nucleocapsids from the nucleus into the cytoplasm is still not fully understood.
Anna D. Dorsch +5 more
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‘Come together’—The Regulatory Interaction of Herpesviral Nuclear Egress Proteins Comprises Both Essential and Accessory Functions [PDF]
Cells, 2022 Herpesviral nuclear egress is a fine-tuned regulatory process that defines the nucleocytoplasmic release of viral capsids. Nuclear capsids are unable to traverse via nuclear pores due to the fact of their large size; therefore, herpesviruses evolved to ...
Sigrun Häge, Manfred Marschall
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RNA helicase DDX3X modulates herpes simplex virus 1 nuclear egress [PDF]
Communications Biology, 2023 DDX3X, a mammalian RNA helicase, modulates herpes simplex virus 1 nuclear egress through cooperating with the viral nuclear egress machinery and the pUS3 viral kinase.
Bita Khadivjam +3 more
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FLARE: A Flow Cytometry–Based Fluorescent Assay for Measuring HSV-1 Nuclear Egress [PDF]
Bio-ProtocolDuring herpesvirus replication, capsids are assembled inside the nucleus and translocated into the cytosol by a non-canonical nucleocytoplasmic export process termed nuclear egress.
Bing Dai +4 more
doaj +2 more sources