Results 171 to 180 of about 136,075 (281)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Dimerization Efficiency of Canine Distemper Virus Matrix Protein Regulates Membrane-Budding Activity. [PDF]

J Virol, 2017
Bringolf F, Herren M, Wyss M, Vidondo B, Langedijk JP, Zurbriggen A, Plattet P.   +6 more
europepmc   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Chemically Driven Division of Protocells by Membrane Budding. [PDF]

J Am Chem Soc
Zambrano P, Chen X, Kriebisch CME, Kriebisch BAK, Zozulia O, Boekhoven J.   +5 more
europepmc   +1 more source

Regulation of the divalent metal ion transporter via membrane budding. [PDF]

Cell Discov, 2016
Mackenzie K, Foot NJ, Anand S, Dalton HE, Chaudhary N, Collins BM, Mathivanan S, Kumar S.   +7 more
europepmc   +1 more source

Drought Risk in Mango and Avocado Orchards: Insights Into Plant Water Relations and Irrigation‐Related Agronomic Solutions

Irrigation and Drainage, EarlyView.
ABSTRACT Climate change is making water availability more uncertain, with growing consequences for the productivity and long‐term sustainability of tropical and subtropical fruit orchards. Mangifera indica L. and Persea americana Mill. both require large amounts of water to sustain growth and productivity.
Eleonora Cataldo
wiley   +1 more source

Oral Cryptococcosis due to Naganishia diffluens in a Patient With Thalassemia: A Case Report and a Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh, Zeynab Haseli, Javad Javidnia, Mahdi Abastabar, Eisa Nazar, Hosein Jalali, Mohamad Taghi Hedayati, Hossein Karami, Mohsen Nosratabadi, Lotfollah Davoodi, Seyyed Reza Aghili, Maryam Moazeni, Iman Haghani, Hamid Badali   +13 more
wiley   +1 more source

Gene expression and metabolic variability in fungus‐resistant PIWI (‘Pilzwiderstandsfähig’) grape cultivars

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Fungus‐resistant PIWI (Pilzwiderstandsfähig) grape cultivars are promising for reducing pesticide inputs in viticulture, but their enological potential is still poorly characterized. We performed a pilot, single‐vintage study integrating berry gene expression and phenolic composition in five Italian red PIWI cultivars (Cabernet ...
Villano Clizia, Luciano Alessandra, Carputo Domenico, Frusciante Luigi, Forino Martino, Napolitano Felice, Smimmo Roberta, Gambuti Angelita, Aversano Riccardo   +8 more
wiley   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo, Ao‐Ying Li, Ting‐Ting Xiang, Zu‐Hao Zhang, Ao Deng, Yang Han   +5 more
wiley   +1 more source

Primula himalayana sp. nov., a new species from eastern Himalaya, India

Nordic Journal of Botany, EarlyView.
Primula himalayana sp. nov., a new species of Primulaceae, is described and illustrated from Tawang, Lutrem, 4238 m a.s.l., Arunachal Pradesh, India. It grows under Juniperus and Berberis scrub forest in an alpine meadow. The new species belong in Primula section Cordifoliae and is resembling P.
Bipankar Hajong, Harsh Singh, Pankaj Bharali   +2 more
wiley   +1 more source